Publications by authors named "Carla C M Medeiros"

Article Synopsis
  • The study investigates the effectiveness of waist-to-height ratio (WHtR) compared to waist circumference (WC) and body mass index (BMI) in identifying youths at risk for cardiometabolic issues.
  • Data from over 34,000 children and adolescents from multiple countries was analyzed, focusing on those with cardiometabolic risk factors, carotid intima-media thickness (cIMT), and arterial stiffness.
  • Results showed that WHtR, WC, and BMI performed similarly in identifying at-risk youths, with WHtR being highlighted as a simple and effective screening tool for clinical use.
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Article Synopsis
  • Metabolic syndrome (MetS) is increasingly common in kids aged 6-17, but existing definitions are complex and hard to use in practice.
  • A new simplified definition was proposed and tested against two established definitions (IDF and NCEP) across 10 global pediatric populations, involving almost 20,000 youths.
  • The simplified definition proved effective in identifying MetS risk, showing good agreement with existing methods and could help pediatricians quickly assess and monitor MetS in various populations for better prevention strategies.
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Objective: To build a model based on cardiometabolic indicators that allow the identification of overweight adolescents at higher risk of subclinical atherosclerotic disease (SAD).

Methods: Cross-sectional study involving 161 adolescents with a body mass index ≥ +1 z-Score, aged 10 to 19 years. Carotid intima-media complex thickness (IMT) was evaluated using ultrasound to assess subclinical atherosclerotic disease.

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Article Synopsis
  • Waist-to-height ratio (WHtR) is being explored as a screening tool for central obesity and cardiometabolic risk in children and adolescents, but a uniform cut-off of 0.50 may not work universally across different countries.
  • A study analyzing data from 24,605 youths aged 6-18 across ten countries found that optimal WHtR cut-offs varied significantly, ranging between the 75th and 95th percentiles and generally clustering regardless of factors like sex and measurement method.
  • For youths in Europe and the US, the optimal WHtR cut-off was around 0.50, while in Asian, African, and South American populations, it was lower at about 0.46, indicating the need
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To assess the effect of exergaming on the microcirculation function of adolescents with overweight or obesity, this non-randomized clinical trial efficacy was conducted with 61 adolescents aged between 10 and 16 years. The intervention group ( = 31) performed exergaming three times per week for 8 weeks. Both groups received guidelines for a healthy diet and staying physically active.

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Objective: The clinical utility of screening for pediatric metabolic syndrome (MetS) in children and adolescents is still controversial. We examined the performance of pediatric MetS vs. clustering of cardiovascular risk factors (which are the components of MetS) for predicting high carotid intima-media thickness (cIMT) in children and adolescents.

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Objective: It has been argued that metabolically healthy obesity (MHO) does not increase cardiovascular disease (CVD) risk. This study examines the association of MHO with carotid intima-media thickness (cIMT), a proxy of CVD risk, in children and adolescents.

Research Design And Methods: Data were available for 3,497 children and adolescents aged 6-17 years from five population-based cross-sectional studies in Brazil, China, Greece, Italy, and Spain.

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Aim: To report an analysis of the concept nursing care of overweight children.

Background: Patient care is the essence of nursing practice. Nursing professionals must define how to serve specific population groups, including overweight children, presenting real solutions to their problem.

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Background: The health benefits of regular physical activity are well documented. However, there are few studies associating this practice with sedentary behavior and cardiovascular risk in adolescents.

Objectives: To evaluate physical activity levels and sedentary behavior and their associations with cardiovascular risk using the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) score

Methods: A cross-sectional study carried out in state-owned public schools in Campina Grande, PB, Brazil, with 576 adolescents aged 15 to 19 years, investigating socioeconomic; demographic; lifestyle; and clinical variables.

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Objective: to verify persistence of metabolic syndrome (MetS) and components in overweight children and adolescents, as well as its relation to socioeconomic and demographic characteristics and to the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) score.

Method: a two-point longitudinal study: at enrollment and after a 24-month interval, with 133 individuals ages from two to 18 years. The demographic anthropomorphic and blood variables were evaluated.

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Objective: to validate the content and appearance of a serial album for children aged from 7 to 10 years addressing the topic of prevention and control of body weight.

Method: methodological study with descriptive nature. The validation process was attended by 33 specialists in educational technologies and/or in excess of infantile weight.

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Background: Obesity is a serious problem of public health and affects all socio-economic groups, irrespective of age, sex or ethnicity. The aim of this study was to evaluate the association between periodontal condition and nutritional status of adolescents.

Methods: This was a cross-sectional study using a probability cluster sampling, and the sample was defined by statistical criterion, consisting of 559 students aged 15-19 yr enrolled in public schools of adolescents of Campina Grande, PB, Brazil in 2012.

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Objective: to analyze the conditions that enhance the dimensions of individual, social and programmatic vulnerability associated with sexually transmitted infections in physically disabled people.

Methods: this transversal study, with a quantitative approach, was conducted in 2015 in conjunction with an association for disabled people in Campina Grande, PB, Brazil. Ninety-eight individuals participated in the study and answered a questionnaire regarding the dimensions of vulnerability in relation to sexually transmitted infections.

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Objective: To evaluate the presence of carotid thickening and its relationship with the Pathobiological Determinants of Atherosclerosis in Youth score.

Methods: We carried out a cross-sectional study involving 512 brazilian adolescents. Variables such as sex, body mass index, concentrations of non-high-density lipoprotein and high-density lipoprotein cholesterol, blood pressure, blood glucose and glycated haemoglobin A1c levels that make up the score, and carotid thickening through the intima-media complex measured by ultrasound were evaluated.

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Objectives: To determine the prevalence of increased serum fibrinogen levels and its association with cardiometabolic risk factors in overweight or obese children and adolescents.

Methods: Cross-sectional study with 138 children and adolescents (overweight or obese) followed at a reference outpatient clinic of the public health care network. Fibrinogen concentration was divided into quartiles, and values above or equal to the third quartile were considered high.

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Aim: To verify the relationship between leptin and cardiometabolic risk factors in obese children and adolescents.

Methods: A cross-sectional study evaluated 200 children and adolescents treated in Campina Grande, Brazil, from April 2009 to March 2010. Leptin, fasting glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides were determined.

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Objective: To review the relationship between lipoprotein (a) [Lp(a)] and other risk factors for cardiovascular disease (CVD) in children and adolescents.

Data Sources: This systematic review included studies from 2001 to 2011, a ten-year time period. Epidemiological studies with children and/or adolescents published in English, Portuguese or Spanish and fully available online were included.

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Objective: to analyze the association between the presence of Acantose nigricans and metabolic changes in overweight adolescents, so as to ascertain the relevance of the identification of this marker in the nursing consultation.

Method: a cross-sectional study undertaken between April 2009 and April 2010 with 118 adolescents who were service users of the Center for Child Obesity in Campina Grande in the Brazilian State of Paraíba (PB). The presence of Acantose nigricans, and the subjects' anthropometric measurements, were investigated.

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Objective: to describe the frequency and the factors associated with cholelithiasis in obese adolescents.

Methods: this was a cross-sectional descriptive study performed with the adolescents between 10 and 19 years of age treated at the Child and Adolescent Obesity Outpatient Clinic from May to December of 2011. Obesity was defined as body mass index (BMI)>P97, and overweight as BMI>P85, for age and gender, according to the 2007 World Health Organization reference.

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The aim of this study was to identify publications in literature that investigated Homocysteine (He) as a risk factor for CVD among children and adolescents. An active search for information in LILACS, IBECS, Science Direct, Medline and Cochrane Library databases was conducted using the following combination of keywords "homocysteine", "cardiovascular diseases", "child" and "adolescent". Fifteen articles were analyzed showing direct relationship with increasing age (8 studies) and male gender (10 studies), and an inverse relationship with serum vitamins B6, B12 and folate levels.

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OBJECTIVE To investigate the association between C-reactive protein (CRP) and high blood pressure (BP) in overweight or obese children and adolescents. METHODS Cross-sectional study with 184 overweight or obese children and adolescents aged from two to 18 years old, from April, 2009 to April, 2010. The classification of nutritional status used the body mass index (BMI).

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Purpose: to identify changes in the food intake patterns among overweight children and teenagers, treated at a reference medical centre.

Method: the method used is that of a cohort study, between April 2010 and April 2011. A total of 109 children and teenagers, either obese or overweight, took part in the study.

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Objective: To investigate the association between serum uric acid concentration according to the presence or absence of non-alcoholic fatty liver disease (NAFLD) and/or metabolic syndrome (MS) in overweight or obese children and adolescents.

Methods: This was a cross-sectional study conducted from April of 2009 to March of 2010, including 129 children and adolescents treated at the Center for Childhood Obesity. Anthropometric data, blood pressure measurements, and laboratory test results were obtained, and NAFLD diagnosis was made by ultrasound.

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Background: Studies have suggested an association between the presence of acanthosis nigricans (AN) and the development of diabetes.

Objective: To investigate the association between AN and insulin resistance (IR) in overweight children and adolescents receiving care at the Center for Childhood Obesity, Campina Grande, PB.

Methods: This cross-sectional study was conducted between April 2009 and April 2010 including 194 individuals of 2 to 18 years of age receiving care within the Brazilian national health network.

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Background: Individuals with insulin resistance are more prone to the development of metabolic syndrome (MS), Type 2 Diabetes Mellitus and Cardiovascular Disease (CVD) OBJECTIVE: To evaluate the association between insulin resistance (IR) and metabolic syndrome components.

Methods: Cross-sectional study of 196 individuals between 2 and 18 years, treated at the Brazilian Public Healthcare system. The association of IR with the MS components was evaluated by Chi-square test, adopting the Homeostasis model assessment-insulin resistance (HOMA-IR) value > 2.

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