Publications by authors named "Carla Andreia Teixeira"
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Synopsis of recent research by authors named "Carla Andreia Teixeira"
- Carla Andreia Teixeira's research primarily focuses on Krabbe's disease, a genetic leukodystrophy characterized by demyelination and axonal degeneration, examining both the underlying mechanisms of neuropathology and potential therapeutic strategies.
- Key findings include early axonal loss in a mouse model (Twitcher mice) prior to demyelination and the potential of bone marrow-derived mesenchymal stromal cells to ameliorate the axonal phenotype and neuropathology associated with the disease.
- The research highlights the challenges in developing effective therapies for leukodystrophies, emphasizing the significance of targeted approaches that address both central and peripheral nervous system involvement.
