Publications by authors named "Carla Alexandra Silva"

Objective: To characterize the health situation of the population in the Imbondeiro neighborhood, sector C (Luanda).

Method: This is a descriptive, cross-sectional and quantitative study. Families living in the sector were included, included in the sample by "door to door" contact.

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Asthma is an allergic disease characterized by inflammation that includes an increase in the number and activation of mast cells in the airways. Glucocorticoids, on the other hand, diminish inflammation as well as the number of mast cells in this disease. Stem cell factor (SCF) is a major growth factor for human mast cells, inducing chemotaxis as well as survival of the mast cells.

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1. Stem cell factor (SCF) is a major growth factor for mast cells, promoting their differentiation and chemotaxis. Its expression is regulated by glucocorticoids in inflammatory conditions, showing an early increased protein expression, before the expected anti-inflammatory decrease (Da Silva et al.

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Expression of stem cell factor SCF, a major mast cell growth factor, is potentiated shortly after co-treatment with interleukin (IL)-1beta and glucocorticoids. SCF promoter contains a GRE-like sequence and a putative kappaB site. We assessed the mechanisms of the regulation of SCF transcription in human lung fibroblasts in culture.

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1. Stem cell factor (SCF) is a major mast cell growth factor that promotes differentiation and chemotaxis of mast cells and inhibits their apoptosis. 2.

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