Publications by authors named "Carla A Ritchie"
[Practical update for the diagnosis and treatment of chronic urticaria].
Medicina (B Aires)
November 2023
Urticaria is a distinctive pattern of inflammatory response of the skin and/or mucous membranes characterized by the sudden appearance of vanishing wheals, angioedema, or both, associated with pruritus. Acute forms are frequent and limited to outbreaks of less than 6 weeks; while the chronic ones have a prevalence of less than 1%, longer duration and can be spontaneous or inducible. The etiopathogenic mechanisms involved in this disease include autoallergy, autoimmunity, and inflammation with cell activation, mainly of the mast cell, leading to its degranulation with the release of vasoactive mediators.
View Article and Find Full Text PDFThe Benefit of Complete Response to Treatment in Patients With Chronic Spontaneous Urticaria-CURE Results.
J Allergy Clin Immunol Pract
February 2023
Article Synopsis
- Chronic spontaneous urticaria (CSU) is a distressing condition affecting patients’ sleep and overall quality of life, as highlighted by findings from the global Chronic Urticaria Registry (CURE).
- Data showed that as patients progressed in treatment, many achieved better control of their symptoms, particularly those with higher Urticaria Control Test (UCT) scores, which were linked to improved sleep and health-related quality of life (HRQoL).
- The study revealed discrepancies between patient-reported measures and physician assessments, indicating that patient-reported outcomes like UCT and UAS7 may provide a more accurate reflection of CSU states compared to physician evaluations.