Publications by authors named "Carl Verhaege"
Acta Cardiol
September 2024
Article Synopsis
- Ticagrelor can be effectively given through a nasogastric tube for patients with acute coronary syndrome (ACS) when they can't take it orally, and it was tested for its effects on platelet inhibition in resuscitated patients and those needing semi-urgent CABG surgery.
- In the study, crushed ticagrelor tablets resulted in significant platelet inhibition, with 89% of resuscitated patients and 85% of CABG patients showing effective results at 24 hours.
- The pharmacokinetics revealed a median time to peak plasma concentration of 100 hours for ticagrelor across both patient groups, indicating that crushed administration maintains its effectiveness and absorption metrics similar to previous research.
