Publications by authors named "Carine Marks"

Introduction: Toxicology students are frequently overwhelmed by the volume and complexity of information. To enhance the learning experience, medical toxicology lecturers created a digital card game named Toxicolitaire™. We sought to explore students' experiences with the online game.

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Methamidophos is a highly hazardous organophosphate and is known to cause an acute cholinergic toxidrome. Methamidophos use is not allowed in South Africa and therefore local data pertaining to methamidophos poisoning is very limited, with no paediatric clinical cases described. Methamidophos is an active metabolite of acephate, a commonly used organophosphate, registered for agricultural use in South Africa.

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Introduction: Snakebites are a neglected tropical disease. In many areas, envenoming incidence and antivenom administration rates are unknown. This study compared antivenom (AV) availability to rates of envenoming and recommendations to treat (RTT) in South Africa.

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Background: Since the start of the coronavirus disease 2019 (COVID-19) pandemic, poison centres worldwide have reported an increase in exposures to chemicals used for infection prevention. Increased availability and use could lead to an increase in exposures. Potential effects on a South African Poison Information Helpline were unknown, therefore a study was performed to describe changes in call volume and profile of poison exposures.

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Article Synopsis
  • The study examines animal poison exposures in South Africa, focusing on data collected from a Poisons Information Helpline over 2.5 years.
  • Findings show that alien plant species were most frequently responsible for poisonings, primarily affecting dogs, while only a small number of cases involved other animals like rabbits and cows.
  • The results highlight the need for better identification of poisonous plants and mushrooms and increased public awareness to prevent animal poisonings.
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Article Synopsis
  • * Analysis of 311 calls revealed that most cases involved adults (81%) and often resulted in minor symptoms, with poisoning from ingestion being more common than envenomation.
  • * The findings suggest that serious cases tend to be reported by healthcare professionals, highlighting the need for public health awareness campaigns about marine-related toxicology.
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Introduction: South Africa has a wide distribution of scorpion species, yet limited data are available regarding the incidence and severity of scorpion envenomation. The aim of this study was to analyse South African epidemiological data of scorpion stings and envenomation as reported to the Tygerberg Poisons Information Centre (TPIC).

Methods: A retrospective analysis was conducted of scorpion-related telephonic consultations to the TPIC over a ten year period (1 January 2005 to 31 December 2014).

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Introduction: Intentional self-poisoning is a significant part of the toxicological burden experienced by emergency centres. The aim of this study was to describe all adults presenting with intentional self-poisoning over a six-month period to the resuscitation unit of Khayelitsha Hospital, Cape Town.

Methods: Adult patients with a diagnosis of intentional self-poisoning between 1 November 2014 and 30 April 2015 were retrospectively analysed after eligible patients were obtained from the Khayelitsha Hospital Emergency Centre database.

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Introduction: The burden of poisoning exposures in Africa is a significant public health concern, yet only ten African countries have poisons information centres. The establishment of poisons centres was subsequently identified as a priority. This article focuses on workshop discussions with international multi-sector stakeholders in Eastern Africa regarding the possibility of a sub-regional poisons centre serving multiple countries.

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