Publications by authors named "Carine Laurence Yehouenou"
Background: Benin's healthcare system is characterized by a lack of local guidelines for surgical antibiotic prophylaxis (SAP), which is essential to prevent surgical site infection.
Aim: To audit compliance for SAP practices in gastrointestinal surgery.
Methods: Data were prospectively collected from gastrointestinal surgery departments in five hospitals.
Article Synopsis
- - The study investigated the presence of antibiotic-resistant genes (ESBL and carbapenemase) in environmental bacteria from two locations in Bobo-Dioulasso, Burkina Faso, focusing on samples from a hospital and a wastewater treatment facility.
- - Out of 180 bacterial isolates collected, 100% were found to produce extended-spectrum beta-lactamases (ESBLs), while 10% produced carbapenemases, with Klebsiella species being the most commonly identified bacteria.
- - Results indicated a significant prevalence of the bla-CTX-M resistance gene, particularly from hospital effluents, suggesting a critical need for effective treatment systems for hospital waste to manage the spread of antibiotic-resistant bacteria in urban areas.
Article Synopsis
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant public health risk, affecting patient health and increasing healthcare costs, prompting a study in six public hospitals in Benin.
- The research involved screening patients and healthcare workers for MRSA, confirming cases through advanced microbiological methods, and utilizing whole-genome sequencing to analyze 27 high-quality MRSA isolates found among the samples collected.
- Findings revealed various strains associated with antimicrobial resistance and identified several virulence genes, emphasizing the necessity for effective strategies to reduce MRSA transmission within hospital settings.
Background: Hand Hygiene (HH) is widely recognized to be one of the most successful and cost-effective measures for reducing the incidence of healthcare-associated infections (HAIs). The hand hygiene behavior of hospital healthcare workers (HCWs) is not well-documented in Benin. Therefore, Theoretical Domains Framework (TDF) was used to identify the behavioral determinants that may impact HCWs' hand-hygiene compliance in a public hospital.
View Article and Find Full Text PDFAn alarming worldwide increase in antimicrobial resistance is complicating the management of surgical site infections (SSIs), especially in low-middle income countries. The main objective of this study was to describe the pattern of carbapenem-resistant bacteria in hospitalized patients and to highlight the challenge of their detection in Benin. We collected pus samples from patients suspected to have SSIs in hospitals.
View Article and Find Full Text PDFWhole-Genome Sequencing-Based Antimicrobial Resistance Characterization and Phylogenomic Investigation of 19 Multidrug-Resistant and Extended-Spectrum Beta-Lactamase-Positive Strains Collected From Hospital Patients in Benin in 2019.
Front Microbiol
December 2021
Article Synopsis
- The rise of extended-spectrum beta-lactamase (ESBL) producing bacteria poses a significant global health threat, particularly linked to high rates of surgical site infections in developing regions with limited antibiotic options.
- This study utilized whole-genome sequencing (WGS) on 19 ESBL-positive bacterial isolates from patients in Benin to analyze their antimicrobial resistance and genetic relationships, revealing 13 different sequence types.
- The findings highlighted a substantial presence of ESBL resistance genes and other resistance factors, emphasizing the utility of WGS for understanding multidrug-resistant bacteria in under-researched environments.
Background: Surgical site infections are related to high morbidity, mortality and healthcare costs. Because the emergence of multidrug-resistant bacteria in hospitals is becoming a worldwide challenge for surgeons who treat healthcare-associated infections, we wished to identify the causative agents involved in these infections and the rate of multidrug-resistant bacteria in six public hospitals in Benin.
Methods: Using standard microbiological procedures, we processed pus specimens collected from obstetrics and gastrointestinal surgery wards.
Hand hygiene in surgery in Benin: opportunities and challenges.
Antimicrob Resist Infect Control
June 2020
Background: Hand Hygiene (HH) has been described as the cornerstone and starting point in all infection control. Compliance to HH is a fundamental quality indicator. The aim of this study was to investigate the HH compliance among Health-care Workers (HCWs) in Benin surgical care units.
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