The trajectory of anxiety symptoms during the transition from childhood to young adulthood is predicted by IQ and sex, but not polygenic risk scores.

Background: Understanding the factors that determine distinct courses of anxiety symptoms throughout development will better guide interventions. There are scarce data-driven longitudinal studies, using multi-modal predictors, investigating the chronicity of anxiety symptoms from childhood to young adulthood, particularly in a middle-income country.

Methods: 2033 youths (ages 6-14 years [Mean age = 10.