Publications by authors named "Carina Rohmer"

Background: The cell envelope of Staphylococcus aureus contains 2 major secondary cell wall glycopolymers: capsular polysaccharide (CP) and wall teichoic acid (WTA). Both CP and WTA are attached to the cell wall and play distinct roles in S. aureus colonization, pathogenesis, and bacterial evasion of host immune defenses.

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Article Synopsis
  • The text discusses the dual nature of certain bacteria that colonize mammalian nasal cavities but can also cause severe infections, highlighting the role of Sa3 phages found in human strains.
  • It emphasizes the importance of specific phage life cycles in different bacterial strains, classifying them into low and high transfer strains based on their ability to replicate phages.
  • The study concludes that the genetic characteristics of the bacterial hosts influence the interactions with phages, which could affect the rate of adaptation and mobilization of bacteria in response to phage presence.
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As an opportunistic pathogen of humans and animals, Staphylococcus aureus asymptomatically colonizes the nasal cavity but is also a leading cause of life-threatening acute and chronic infections. The evolution of S. aureus resulting from short- and long-term adaptation to diverse hosts is tightly associated with mobile genetic elements.

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