Effect of sweetener containing Stevia on the development of dental caries in enamel and dentin under a microcosm biofilm model.

Objective: This study compared the effect of commercial and pure sweetener containing stevia to that of aspartame, to sucrose and xylitol on the development of dental caries.

Methods: 228 bovine enamel and root dentin were exposed to microcosm biofilm model using human saliva. From the 2 to the 5 day, the samples were exposed daily to McBain saliva supplemented with 0.