Publications by authors named "Care W"

Bed bugs are pervasive global pests that have reemerged in the last 20 years as a significant public health concern, especially in densely populated urban areas. Beyond financial losses, expenses, inconvenience, and psychological distress, bed bug infestations often necessitate chemical management, posing poisoning risks to those with an infestation. The French Poison Control Centers recorded 1056 cases of exposure to bed bug insecticide products between 1999 and 2021.

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  • In 2023, two deaths in the U.S. were linked to uncooked morel mushrooms, marking a concerning increase in severe gastrointestinal toxicity reports associated with their consumption.
  • An analysis of cases from the French National Database showed that a significant percentage of morel exposure resulted in gastrointestinal (83.6%) and neurological (53.3%) symptoms, with some cases leading to shock and fatalities.
  • The shift from wild to cultivated morels in sales may contribute to more severe poisoning cases, emphasizing the need for cautious consumption and increased awareness about the risks, especially with raw or undercooked mushrooms.
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  • Recreational use of nitrous oxide (NO) has led to a rise in severe neurological disorders, particularly affecting young adults in economically disadvantaged areas.
  • The study analyzed 181 patients, noting a significant incidence increase in 2020-2021, especially in those aged 20-25.
  • Compared to other inflammatory neurological disorders, NI-NDs were found to be two to three times more common in these vulnerable populations.
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Introduction: The short message service is an alternative to telephone follow-up of exposure cases reported to poison centres. The aim of this study was to compare the proportion of exposure cases successfully followed up and the respective cost of telephone and short message service follow-up between two poison centres, one using both methods of follow-up (Paris centre) and the other using telephone follow-up only (Nancy centre).

Methods: In 2021, we included cases eligible for short message service follow-up at both centres.

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Amatoxin-containing mushroom poisoning occurs after consumption of certain mushroom species, of the genera Amanita, Lepiota and Galerina. Amanita phalloides is the most implicated species, responsible for over more than 90% of mushroom-related deaths. The α-amanitin is responsible for most of the observed effects.

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Aim: To describe the symptoms, patient demographics, and trends over time of adverse drug reactions (ADRs) related to weak opioid analgesics reported to the French vigilance networks.

Methods: Retrospective study of data from French Poison Control Centers and Pharmacovigilance Centers databases of weak opioid analgesics-related ADRs cases, with high causality score, in adults, in therapeutic analgesic use, without co-exposure, between 2011 and 2020.

Results: The number of cases was 388 in the Poisonings database and 155 in the Pharmacovigilance database; ratio of the number of these cases to all reported cases during the study period was 0.

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Serum sickness (SS) and anaphylaxis are well-documented complications of rituximab (RTX) infusions. While the first presents usually as a triad of fever, rash, and arthralgias occurring seven to 14 days after infusion, the second presents as a sudden onset of hemodynamic instability, bronchospasm, and a pruritic erythematous rash, occurring within the first few hours after infusion. We present here a case of serum sickness associated with anaphylaxis five days after the first infusion of a second course of RTX.

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  • Licorice refers to a plant and its roots, especially Glycyrrhiza glabra, which is widely used in herbal medicine, food, cosmetics, and pharmaceuticals.
  • Glycyrrhizin, a key component of licorice, is processed in the body into metabolites that can lead to health issues like apparent mineralocorticoid excess syndrome, particularly after chronic high doses.
  • Symptoms of glycyrrhizin poisoning include hypertension and fluid retention, and the diagnosis involves clinical evaluation and lab tests, with treatment focusing on symptom relief and discontinuing licorice use.
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Introduction: Clinical expression of cytomegalovirus (CMV) infection is numerous and depends on the immune status of the host. In immunocompromised patients, CMV disease corresponds to reactivation of the virus with tissue damage responsible for significant morbidity and mortality. In immunocompetent adults, primary CMV infection is usually asymptomatic but may rarely result in severe organ damage.

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Sixty-seven scorpion species have been described in France and its territories, where they have been found to be heterogeneously distributed. Indeed, only one species can be found on Réunion Island, while 38 species exist in French Guiana. The number of stings is also heterogenous, with up to 90 stings per 100,000 inhabitants occurring annually.

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Introduction: Recreational use of nitrous oxide (NO) is increasing in Western countries, including France. During the COVID-19 pandemic, some authors warned that recreational NO use could increase further as the supply of illicit drugs was impacted by various containment measures.

Methods: We retrospectively analyzed NO exposures reported to the Paris Poison Control Center (France) from 2010/01/01 to 2021/04/15.

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Introduction: Assessment of the medical fitness to serve in the armed forces has two objectives: to prevent the military operations from being jeopardized by a medical issue, and to protect soldiers from the sequelae of diseases that could become complicated in the operational field, especially in overseas operations where soldiers are exposed to a remote setting and a long evacuation time. Little is known about fitness decisions for soldiers with systemic or autoimmune diseases. Therefore, we conducted a single-center retrospective study of internal medicine fitness decisions.

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Introduction: In recent years, the number of patients managed by poison control centres (PCCs) has increased without a proportional increase in the number of physicians. To improve efficiency without neglecting patient follow-up, some PCCs have begun using text messages. We evaluated the difference in response rates between text messaging and traditional telephone follow-up.

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Introduction: Data regarding immediate-release (IR)-tramadol exposures in children remain sparse. We aimed to investigate the incidence of IR-tramadol exposures in ≤6-year-old children, to describe the characteristics and resulting outcome of ingestions involving IR-tramadol alone, and to estimate a clinically relevant toxic dose in this population.

Methods: Retrospective analysis of IR-tramadol exposures in ≤6-year-old children, collected by the French Poison Control Centers (PCCs) in 2003-2019.

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Nitrous oxide (NO) is used since the eighteenth century as an anesthetic and analgesic but also for recreational use. If the labelled uses of NO and their modalities are nowadays perfectly framed, the misuse of NO takes very alarming proportions among teenagers and young adults. This misuse is the cause of acute (hypoxia, barotrauma, burns, neuropsychiatric disorders) and chronic complications if repeated (myeloneuropathy, anemia, thrombosis, inhalant use disorder).

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Rationale: Superabsorbent polymers are marketed as toys, and cases of ingestion in children are increasingly reported. Even if these cases are usually considered benign, bowel obstruction has been reported.

Objective: To investigate the exposure characteristics, clinical presentation, management, and outcome of patients who developed bowel obstruction following ingestion of superabsorbent polymer-made products.

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Workplace violence directed at nurses in healthcare settings is a common occurrence across the globe resulting in negative nurse and organizational implications that may impact the quality of care provided. Psychiatric nurses working on acute care psychiatric units are at an increased risk and are frequently subjected to patients' violent and aggressive behaviors. These implications pose significant threats to the nurses' emotional, physical, and psychological health.

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Aim: To investigate the role stressors, and how coping strategies cultivated nurse managers' resilience in rural workplaces.

Background: A stressful workplace can impair the mental and physical health of nurse managers leading to poor performance. Building and sustaining manager resilience in complex and stressful practice environments is necessary to attract and maintain competent and skilled managers.

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Introduction: Misuse/abuse of pregabalin is increasing worldwide. French Poison Control Centers (PCCs) recently received several unusual calls regarding the recreational use of pregabalin in adolescents. This study aims to describe this new and specific population of pregabalin misusers.

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