Publications by authors named "Cara Wiest"

Article Synopsis
  • The study examined the effects of pulmonary embolism response teams (PERTs) on patient outcomes by comparing data from three years before and after their implementation at a specific hospital.
  • It found that despite an increase in risk assessment methods post-PERT, there was no significant difference in pulmonary embolism-related mortality rates (2.6% pre-PERT vs 2.9% post-PERT).
  • Also, while the overall use of advanced therapies remained the same, the utilization patterns changed, with a decrease in systemic thrombolysis and an increase in catheter-directed therapy after PERT implementation.
View Article and Find Full Text PDF

Unlabelled: Hospitalized acute medically ill patients with a history of venous thromboembolism (VTE) are at increased risk for recurrent VTE. We characterized the efficacy and safety of betrixaban for prevention of recurrent VTE in these high risk patients. The APEX trial randomized 7513 acutely ill hospitalized medical patients at risk for developing VTE to receive either betrixaban for 35-42 days or enoxaparin for 10 ± 4 days to prevent VTE.

View Article and Find Full Text PDF

Purpose: Corneal involvement in mitochondrial disease is seldom described. Kearns-Sayre syndrome (KSS) is a mitochondrial disorder characterized by retinitis pigmentosa, external ophthalmoplegia, and heart block. We report 2 patients with KSS with corneal lesions involving the endothelium, which improved with Coenzyme Q10 (CoQ10).

View Article and Find Full Text PDF