Self-management in type 2 diabetes: the adolescent perspective.

Purpose: The purpose of this study was to document barriers and facilitators of self-management as perceived by adolescents with type 2 diabetes.

Methods: Focus groups were conducted with adolescents diagnosed with type 2 diabetes. Adolescents aged 13 to 19 years were recruited from an academic medical center diabetes clinic.

Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib.

Purpose: To evaluate the efficacy and toxicity of combined treatment with two targeted agents, an antibody against vascular endothelial growth factor (bevacizumab) and an epidermal growth factor receptor tyrosine kinase inhibitor (erlotinib), in the treatment of patients with metastatic clear-cell renal carcinoma.

Patients And Methods: Sixty-three patients with metastatic clear-cell renal carcinoma were treated with bevacizumab 10 mg/kg intravenously every 2 weeks and erlotinib 150 mg orally daily. Patients were reevaluated after 8 weeks of treatment; patients who responded continued treatment until they experienced tumor progression.