Publications by authors named "Cara Barnes"

Background: Baseline right bundle branch block (RBBB) is an established predictor of permanent pacemaker (PPM) requirement after transcatheter aortic valve replacement (TAVR). There are limited data to support prophylactic PPM implantation in advance of TAVR. We aimed to evaluate the efficacy and safety of prophylactic PPM implantation in patients with RBBB prior to TAVR, and to identify the predictors of pacing dependence after TAVR.

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Article Synopsis
  • Severe secondary mitral regurgitation has a high mortality rate, with about 20% of patients dying within a year of diagnosis, but there are effective therapies available to improve patient outcomes.
  • Guideline-directed medical therapy can significantly reduce the severity of mitral regurgitation in 40-45% of patients and can lead to earlier referrals for other interventions, like device therapy.
  • Key treatments include managing atrial fibrillation, using cardiac resynchronization devices, and considering mitral valve interventions like transcatheter edge-to-edge repair (TEER), which can effectively reduce hospitalizations and mortality in carefully selected patients but is still underutilized in some regions.
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Objective: We tested the hypothesis that patients with a potential acute coronary syndrome (ACS) and very low levels of high-sensitivity cardiac troponin I can be efficiently and safely discharged from the emergency department after a single troponin measurement.

Methods: This prospective cohort study recruited 2255 consecutive patients aged ≥18 years presenting to the Emergency Department, Royal Perth Hospital, Western Australia, with chest pain without high-risk features but requiring the exclusion of ACS. Patients were managed using a guideline-recommended pathway or our novel Single Troponin Accelerated Triage (STAT) pathway.

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Background: Atrial fibrillation (AF) secondary to non-cardiac surgery and medical illness is common and, although often transient, is associated with an increased risk of stroke and mortality. This pilot study tested the feasibility of self-monitoring to detect recurrent AF in this setting and the frequency with which it occurred.

Methods: Patients with new secondary AF after non-cardiac surgery or medical illness that reverted to sinus rhythm before discharge were recruited in three tertiary hospitals in Australia.

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Background: Anticoagulated patients who need to undergo endoscopy present unique challenges to the gastroenterologist. The continuation of anticoagulant therapy increases the risk of haemorrhagic complications of gastrointestinal endoscopy. Reversing the anticoagulation increases the risk of thromboembolism.

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