Construction and validation of a readmission risk prediction model for elderly patients with coronary heart disease.

Background: To investigate the risk factors for readmission of elderly patients with coronary artery disease, and to construct and validate a predictive model for readmission risk of elderly patients with coronary artery disease within 3 years by applying machine learning method.

Methods: We selected 575 elderly patients with CHD admitted to the Affiliated Lu'an Hospital of Anhui Medical University from January 2020 to January 2023. Based on whether patients were readmitted within 3 years, they were divided into two groups: those readmitted within 3 years (215 patients) and those not readmitted within 3 years (360 patients).

Effect of sac transection versus sac reduction on seroma in laparoscopic indirect hernia repair: a systematic review and meta-analysis.

Background: Seroma formation is a prevalent postoperative complication following laparoscopic inguinal hernia repair. While seromas are mostly self-absorbed, they can cause discomfort for the patient and complicate the assessment of hernia recurrence. Two primary techniques for managing the hernia sac are sac transection and complete sac reduction.

Inhalation of patchouli essential oil alleviates airway inflammation in cigarette smoke-induced COPD mice.

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide, characterized by persistent respiratory symptoms and airflow limitations resulting from small airway injury, bronchial wall thickening, and hypersecretion of mucus. Current pharmacological interventions are ineffective in reversing these airflow limitations; In our study, we investigated the potential role of patchouli essential oil (PEO) in the treatment of COPD and its underlying molecular mechanisms, both in vitro and in vivo. To establish a cigarette smoke-induced COPD mice model, we exposed the mice to cigarette smoke (CS) and administered nasal drip of lipopolysaccharides (LPS).

[Finite element analysis of influence of humerus torque screw tip distance on stability of proximal humeral fracture plate fixation].

Objective: To explore changes of humerus torque screw tip distance on stability of proximal humeral internal locking system (PHILOS) by finite element analysis, in order to provide reference for selection of intraoperative plant size.

Methods: The proximal humerus 3D model was constructed based on Synbone artificial bone model in 3D engineering drawing software, and the corresponding 3D model was constructed based on PHILOS bone plate contour. The model was modified to simulate comminuted proximal humerus fracture, and the operation model was simulated after fracture, and the fixed operation model was assembled, the apex distance of humerus moment screw was set as 4, 8, 12 and 16 mm respectively.

Effects of Visualized Health Education Based on Health Belief Model on Self-Management of Patients Undergoing Maintenance Hemodialysis.

Background: Patients with end-stage renal disease often require maintenance hemodialysis (MHD). Effective self-management is crucial for the prognosis of patients undergoing MHD; however, their self-management practices remain suboptimal.

Objective: This study aimed to explore the effects of visualized health education based on health belief model on self-management, self-efficacy, quality of life, and quality of dialysis in patients undergoing MHD.

Regulation of multilayer long crystalline MoS by NiO-modified AlO for improved hydrodesulfurization of COS.

Activated alumina-based composite oxide support is a commonly used support in hydrodesulfurization (HDS) catalysts, which not only retains the performance advantages of each component in the composite oxide support, but also significantly improves the defects of a single activated alumina support, such as the strong metal-support force of interaction. In this study, NiO-AlO composite support was prepared by introducing NiO-modified AlO, and MoS/NiO-AlO catalysts were prepared for the hydrodesulfurization of COS by liquid phase reduction method. In the COS hydrogenation reaction, the MoS/NiO-AlO catalyst achieved complete conversion of COS at 220 °C and showed more than 99.

Total Alkaloids of Rhizoma Corydalis regulates gut microbiota and restores gut immune barrier to ameliorate cognitive dysfunction in diabetic rats.

Background And Objectives: Given the widespread dysbiosis of gut microbiota in patients with T2DM, it has been found that the microbiota-gut-brain axis plays an influential regulatory role in diabetic cognitive dysfunction, and improving gut dysbiosis may be a potential strategy for treating diabetic cognitive dysfunction. Total Alkaloids of Rhizoma Corydalis (TAC) is the main active component extracted from Rhizoma Corydalis. Pharmacological studies have demonstrated its significant pharmacological effects on the cardiovascular and cerebrovascular systems, and berberine, the main component of TAC, has a certain regulatory effect on gut microbiota.

Optical-resolution parallel ultraviolet photoacoustic microscopy for slide-free histology.

Intraoperative imaging of slide-free specimens is crucial for oncology surgeries, allowing surgeons to quickly identify tumor margins for precise surgical guidance. While high-resolution ultraviolet photoacoustic microscopy has been demonstrated for slide-free histology, the imaging speed is insufficient, due to the low laser repetition rate and the limited depth of field. To address these challenges, we present parallel ultraviolet photoacoustic microscopy (PUV-PAM) with simultaneous scanning of eight optical foci to acquire histology-like images of slide-free fresh specimens, improving the ultraviolet PAM imaging speed limited by low laser repetition rates.

DUPAN-2 in pancreatic cancer: Systematic review and meta-analysis.

Objective: Pancreatic cancer (PC) is a highly aggressive malignancy with poor prognosis and high mortality rate. Identifying reliable biomarkers for the early diagnosis and treatment is urgently needed. This study aims to comprehensively evaluate the diagnostic and prognostic value of DUPAN-2 in PC through a meta-analysis.

An Electrochemical Screening Reactor Kit for Rapid Optimization of Electrosynthesis Applications.

Electrosynthetic processes powered by renewable energy present a viable solution to decarbonize the chemical industry, while producing essential chemical products for modern society. However, replacing well-established thermocatalytic methods with renewable-powered electrosynthesis requires cost-efficient and highly optimized systems. Current optimization of electrolysis conditions towards industrial applications involving scalable electrodes is time-consuming, highlighting the necessity for the development of electrochemical setups aimed at rapid and material efficient testing.

Electrocatalytic hydrogen evolution reaction with a Cu porphyrin bearing -CF substituents.

Cu tetrakis(trifluoromethyl)porphyrin (1) was synthesized and examined as an electrocatalyst for the hydrogen evolution reaction (HER). We showed that 1 is highly efficient for the electrocatalytic HER in acetonitrile with trifluoroacetic acid (TFA) and outperforms Cu tetrakis(pentafluorophenyl)porphyrin (2) by decreasing the onset overpotential by 220 mV. The / value ( is the catalytic peak current and is the non-catalytic peak current) with 1 is 97, while it is 53 with 2.

Scaling up electrochemical CO reduction: enhancing the performance of metalloporphyrin complexes in zero-gap electrolyzers.

Metalloporphyrins are widely studied in the field of electrochemical CO reduction (COR), with the main focus on homogenous catalysis. Herein, six metalloporphyrins (M = Fe, Co, Ni, Cu, Zn, Ag) were incorporated in gas diffusion electrodes and used in zero-gap electrolyzers to reach varying FEs for CO of <1% (Fe,Ni), 11% (Cu), 37% (Zn), 75% (Co) and nearly 100% (Ag) at a current density of 50 mA cm.

Unlocking the Activity of Molecular Assemblies for CO Electroreduction in Zero-Gap Electrolysers via Catalyst Ink Engineering.

In recent years, CO electrolysis, particularly the electrochemical reduction of CO to CO in zero-gap systems, has gained significant attention. While Ag-coated gas diffusion electrodes are commonly used in state-of-the-art systems, heterogenized molecular catalysts like bis-coordinated homoleptic silver(I) N,N-bis(arylimino)-acenaphthene (Ag-BIAN) complexes are emerging as a promising alternative due to their tunability and high mass activity. In this study, the influence of ink composition on the performance of Ag-BIAN-based GDEs in zero-gap electrolyzers (ZGEs) are systematically explored at 60 °C and 600 mA cm⁻.

The Effect of Mother's Mediation on Sibling Conflict Among Chinese Children.

Thirty-four Chinese families (each consisting of a mother and two children) were recruited to participate in this study. The firstborn children had an average age of 12.00 ± 2.

The potential influence and intervention measures of gut microbiota on sperm: it is time to focus on testis-gut microbiota axis.

As the global male infertility rate continues to rise, there is an urgent imperative to investigate the underlying causes of sustained deterioration in sperm quality. The gut microbiota emerges as a pivotal factor in host health regulation, with mounting evidence highlighting its dual influence on semen. This review underscores the interplay between the Testis-Gut microbiota axis and its consequential effects on sperm.

Childbearing Histories and Midlife Cognition: Accounting for Early Life Factors.

Objectives: Childbearing histories-for example, parity and age at first birth-matter for the health outcomes of mid- and later-life women. There is growing evidence that childbearing may shape cognitive outcomes. However, previous research is not definitive due to its inability to account for selection.

Mo-Doped α-MnO for Enhanced Electrocatalytic Water Oxidation.

Manganese is a key metal involved in the catalysis of natural photosynthesis. Thus, the investigation of Mn-based electrocatalysts for water oxidation is of high importance. This work reports the doping of Mo into α-MnO nanorods to improve the water oxidation performance.

Clusterin from endometrial glands plays a critical role in decidualization via Trem2.

Background: Decidualization is a critical step in establishing pregnancy in mammals. Successful decidualization depends on intricate gland-stromal crosstalk. Clusterin (Clu) is a ubiquitously secreted protein in physiological fluids that is involved in numerous physiological functions.

Feasibility study of opportunistic osteoporosis screening on chest CT using a multi-feature fusion DCNN model.

Unlabelled: A multi-feature fusion DCNN model for automated evaluation of lumbar vertebrae L1 on chest combined with clinical information and radiomics permits estimation of volumetric bone mineral density for evaluation of osteoporosis.

Purpose: To develop a multi-feature deep learning model based on chest CT, combined with clinical information and radiomics to explore the feasibility in screening for osteoporosis based on estimation of volumetric bone mineral density.

Methods: The chest CT images of 1048 health check subjects were retrospectively collected as the master dataset, and the images of 637 subjects obtained from a different CT scanner were used for the external validation cohort.

Ethionine-induced S-adenosylmethionine deficiency suppressed H3K27me3 and cell differentiation during neural tube development in mice.

S-adenosylmethionine (SAM) as a major methyl donor plays a key role in methylation modification in vivo, and its disorder was closely related to neural tube defects (NTDs). However, the exact mechanism between SAM deficiency and NTDs remained unclearly. Hence, we investigated the association between histone methylation modification and cell differentiation in NTDs mice induced by SAM deficiency.