Using new careers in nursing research findings to develop an evidence-based pre-entry immersion program.

Background: New Careers In Nursing (NCIN) data analysis results were used to inform the development of The Bridge to Nursing Success Program (Bridge). NCIN data revealed that participation in a pre-entry immersion program (PIP) was associated with higher rates of retention and graduation.

Purpose: The purpose of this article is to 1).

making technology talk: how interoperability can improve care, drive effidcincy, and reduce waste.

Health systems and providers that search out more interoperable technology can help move the industry toward greater productivity using a multistep approach. Assemble a team of champions to address the interoperability issue. Describe the desired state of interoperability for the organization.

Acute delirium: differentiation and care.

The health care costs for patients with delirium were estimated to be more than double the costs for patients without delirium and potentially exceeded the costs for falls, diabetes mellitus, and hip fractures; yet the fluctuating nature of the condition makes it a difficult condition for health professionals to recognize and treat. The key, then, is in recognition and prevention.

Adeno-associated virus serotype 2 induces cell-mediated immune responses directed against multiple epitopes of the capsid protein VP1.

Adeno-associated virus serotype 2 (AAV-2) has been developed as a gene therapy vector. Antibody and cell-mediated immune responses to AAV-2 or AAV-2-transfected cells may confound the therapeutic use of such vectors in clinical practice. In one of the most detailed examinations of AAV-2 immunity in humans to date, cell-mediated and humoral immune responses to AAV-2 were characterized from a panel of healthy blood donors.

Chicken suprachiasmatic nuclei: II. Autoradiographic and immunohistochemical analysis.

The vertebrate circadian system is composed of multiple inputs, oscillators, pacemakers, and outputs. In birds, the pineal gland and retinae have been defined as pacemakers within this system. Evidence for a third, hypothalamic pacemaker is abundant.

Chicken suprachiasmatic nuclei: I. Efferent and afferent connections.

The avian circadian system is composed of multiple inputs, oscillators, and outputs. Among its oscillators are the pineal gland, retinae, and a hypothalamic structure assumed to be homologous to the mammalian suprachiasmatic nucleus (SCN). Two structures have been suggested as this homolog -- the medial SCN (mSCN) and the visual SCN (vSCN).

Daily and circadian fluctuation in 2-deoxy[(14)C]-glucose uptake in circadian and visual system structures of the chick brain: effects of exogenous melatonin.

Previous studies show that several structures of the house sparrow visual system are metabolically rhythmic, as determined by 2-deoxy[(14)C]glucose (2DG) uptake, and that these metabolic rhythms depend upon rhythmic melatonin in this species. In many species of birds, high affinity binding of 2[(125)I] iodomelatonin is widespread in the brain, especially in visual system structures. The present study asks whether 2DG uptake is similarly rhythmic in the chick brain and whether exogenous melatonin administration affects 2DG uptake.

Mars scientific investigations as a precursor for human exploration.

In the past two years, NASA has begun to develop and implement plans for investigations on robotic Mars missions which are focused toward returning data critical for planning human missions to Mars. The Mars Surveyor Program 2001 Orbiter and Lander missions will mark the first time that experiments dedicated to preparation for human exploration will be carried out. Investigations on these missions and future missions range from characterization of the physical and chemical environment of Mars, to predicting the response of biology to the Mars environment.

Double-blind, placebo-controlled study of amantadine hydrochloride in the treatment of children with autistic disorder.

Objective: To test the hypothesis that amantadine hydrochloride is a safe and effective treatment for behavioral disturbances--for example, hyperactivity and irritability--in children with autism.

Method: Thirty-nine subjects (intent to treat; 5-19 years old; IQ > 35) had autism diagnosed according to DSM-IV and ICD-10 criteria using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule-Generic. The Aberrant Behavior Checklist-Community Version (ABC-CV) and Clinical Global Impressions (CGI) scale were used as outcome variables.

Nosocomial enterococcal infections in children.

Objectives: To identify factors that are associated with an increased risk of nosocomial enterococcal infection in children.

Methods: A matched case-control study was conducted between January 1989 and July 1993 at the Children's National Medical Center, Washington DC. One control patient for each case was identified.

Effect of several interventions on the frequency of handwashing among elementary public school children.

Background: The purpose of this educational project was to assess the effect of several interventions on the frequency of handwashing among elementary public school children.

Methods: Participants in this project were first-graders and fourth-graders from jurisdictions within a mid-Atlantic metropolitan area. Phase I included a baseline assessment of bathroom cleanliness as well as adequacy of supplies for handwashing in each school.

Survey of current hospital preceptorship programs in the greater Philadelphia area.

A survey of acute care hospitals in the five-county Philadelphia area was conducted to gather data on the number of preceptorship programs, the reason for their initiation and continuance, and similarities and differences in structure, process, content, and outcomes. A nonexperimental descriptive design was used. A 25-item original questionnaire consisting of both closed and open-ended questions was mailed to 60 acute care hospitals.

An outbreak of Staphylococcus epidermidis septicemia.

During 45 wk from August 1980 to June 1981, the catheter sepsis rate increased from a prior 2 to 34% (23 of 68 patients on intravenous hyperalimentation). The causative organism was Staphylococcus epidermidis, grown on blood cultures in 21 of the 23 patients and on the catheter-tips of all 23. Routine cultures of the catheter-tips of the 45 patients who received intravenous hyperalimentation during this period with no evidence of catheter sepsis grew S.