Publications by authors named "Canto G"
Background: High-grade gliomas (HGG) are the most aggressive primary brain tumors with poor prognoses despite conventional treatments. Immunotherapy has emerged as a promising avenue due to its potential to elicit a targeted immune response against tumor cells.
Objective: This meta-analysis aimed to evaluate the efficacy and safety of various immunotherapeutic strategies, including immune checkpoint inhibitors (ICI), virotherapy, and dendritic cell vaccines (DCV) in treating HGG.
Objective: To systematically review studies on the effects of early stimulation on the neuropsychomotor development of children with microcephaly.
Data Source: A systematic review was conducted in PubMed/MEDLINE, Virtual Health Library, and Cochrane Library databases. Studies that addressed the use of early stimulation in playful and interactive environments in children with microcephaly were included.
Background: Non-nutritive sucking habits likely may cause occlusal changes such as anterior open bite (AOB) if they persist over extended time.
Objectives: To assess if there is self-correction of AOB after cessation of non-nutritive sucking habits in children older than 4 years old, through a systematic review.
Search Methods: Data sources included PubMed, Scopus, Web of Science and Latin American and Caribbean Health Sciences (LILACS) databases, gray literature as Google Scholar, the database System for Information on Gray Literature in Europe (OpenGrey) and ProQuest Dissertations and Theses Database, also hand searches of the included studies references.
Objectives: This systematic review aimed to answer the following question 'What are the worldwide prevalence of SARS-CoV-2 infection and associated factors among oral health-care workers (OHCWs) before vaccination?'
Methods: Seven databases and registers as well as three grey databases were searched for observational studies in the field. Paired reviewers independently screened studies, extracted data and assessed the methodological quality. Overall seroprevalence for SARS-CoV-2 infection was analysed using a random-effect model subgrouped by professional category.
Article Synopsis
- The study investigated how parents accept various pediatric behavior guidance techniques (BGTs) used during dental visits for their children, comparing responses from parents of both special health care needs (SHCN) and non-special health care needs (non-SHCN) children.
- A total of 53 studies with 4,868 participants were analyzed, showing a wide range of acceptance rates, from 85.6% for the tell-show-do technique down to only 25.7% for passive protective stabilization among non-SHCN parents.
- Overall, the findings indicate that parents generally prefer simpler BGTs over more complex methods, but the heterogeneity among studies leads to low confidence in the conclusions.
Article Synopsis
- The study investigated the potential link between specific genetic variations in the melatonin receptor type 1A gene and sleep bruxism in a Brazilian population.
- Participants underwent polysomnography to assess sleep issues, and DNA was collected for analysis of three single nucleotide polymorphisms (SNPs).
- The results showed no significant association between these SNPs and sleep bruxism, indicating that they are unlikely to play a role in this condition among the studied individuals.
Background: Allergy can start at early ages, with genetic and environmental factors contributing to its development.
Aim: The study aimed to describe the pattern of sensitisation and allergy in children and adolescents of Spanish versus Moroccan ancestry but born in the same rural area of Spain.
Methods: Participants were children and adolescents (3-19 years) of Spanish or Moroccan descent, born in Blanca, Murcia (Spain).
Objective: Burnout syndrome has negative consequences on the dentist's health and performance during work. This systematic review aimed to assess the prevalence of Burnout syndrome in dentists.
Methods: Searches were carried out in Medline, Scopus, Web of Science, PsycINFO, EMBASE, LILACS databases, and searches in the gray literature on January 27, 2021.
Antibiotic Resistance in Paediatric Febrile Urinary Tract Infections.
J Glob Antimicrob Resist
June 2022
Febrile urinary tract infection (UTI) is currently considered the most frequent cause of serious bacterial illness in children in the first 2 years of life. UTI in paediatrics can irreversibly damage the renal parenchyma and lead to chronic renal insufficiency and related problems. To avoid this risk, an early effective antibiotic treatment is essential.
View Article and Find Full Text PDFThe most important peach fruit allergen is Pru p 3, followed by Pru p 1, Pru p 4, and Pru p 7. We aimed to assess their role in subjects with peach fruit-induced allergy (anaphylaxis and OAS) and compare skin prick tests (SPT) vs. specific immunoglobulin E (sIgE) for predicting anaphylaxis.
View Article and Find Full Text PDFObjective: To analyze the underdiagnosis of COVID-19 through nowcasting with machine learning in a Southern Brazilian capital city.
Methods: Observational ecological design and data from 3916 notified cases of COVID-19 from April 14th to June 2nd, 2020 in Florianópolis, Brazil. A machine-learning algorithm was used to classify cases that had no diagnosis, producing the nowcast.
Objective: To review the literature about children's and parent's perceptions on surgical attire.
Data Source: A systematic search was conducted in the databases EMBASE, Latin American and Caribbean Health Sciences (LILACS), PubMed, PsycINFO, Scopus and Web of Science. Grey literature was searched on Google Scholar, Open Grey and ProQuest Dissertations, and Theses Database.
Cross-hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is a relatively common, non-allergic, adverse drug event triggered by two or more chemically unrelated NSAIDs. Current evidence point to COX-1 inhibition as one of the main factors in its etiopathogenesis. Evidence also suggests that the risk is dose-dependent.
View Article and Find Full Text PDFBackground: The World Allergy Organization and the European Academy of Allergy and Clinical Immunology recommend to perform product-specific meta-analyses for allergen-specific immunotherapies because of the high degree of heterogeneity between individual products. This meta-analysis evaluates the efficacy and safety of Glutaraldehyde-modified and MCT (MicroCrystalline Tyrosine)-adsorbed allergoids (MATA).
Methods: The databases MEDLINE, LILACS, embase, LIVIVO, Web of Science and Google (Scholar) were searched for publications on MATA up to June 2019.
Purpose: The objective of this systematic review was to answer the question: "Is there association between obstructive sleep apnea (OSA) and health-related quality of life (HRQoL) in untreated adults?"
Methods: We included observational studies that evaluated the health-related quality of life of patients with OSA vs control groups, through generic and disease-specific questionnaires. The searches were conducted in six databases: Embase, Lilacs, PsycINFO, PubMed, Scopus, and Web of Science. Additional search in the grey literature and hand search were performed, and also experts were consulted.
Background And Purpose: Cross-reactive hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) is a relatively common adverse drug event caused by two or more chemically unrelated drugs and that is attributed to inhibition of the COX activity, particularly COX-1. Several studies investigated variations in the genes coding for COX enzymes as potential risk factors. However, these studies only interrogated a few single nucleotide variations (SNVs), leaving untested most of the gene sequence.
View Article and Find Full Text PDFOccupational Rhinitis Due to Inhaled Locust Bean Gum: Cross-Reactivity With Legumes and Nuts.
J Investig Allergol Clin Immunol
October 2020
Article Synopsis
- The review explores the connection between obesity and periodontal diseases, focusing on inflammatory markers in serum, saliva, and gingival crevicular fluid (GCF), and how they relate to obesity and periodontitis statuses in adults.
- Out of 832 studies reviewed, 21 were qualitatively analyzed and 15 quantitatively assessed, revealing that adults with both obesity and periodontitis (O+P+) had significantly higher levels of certain inflammatory markers compared to those without periodontitis or obesity.
- Although the quality of the studies was mostly acceptable, the overall evidence supporting the link between these conditions and inflammatory markers was graded as very low to moderate, with additional nuances in potential biomarkers still needing exploration.
Background: The authors' objective in this systematic review was to investigate the barriers involved in the application of evidence-based dentistry principles, as reported by dentists. The authors registered the protocol in the PROSPERO database.
Types Of Studies Reviewed: Eligible studies included qualitative and quantitative approaches, constituting information about barriers, collected through interviews, questionnaires, or conversation sessions.
Article Synopsis
- The study aimed to compare carotid plaque characteristics in patients living at high altitude (Xining) versus those at sea level (Jinan) using magnetic resonance imaging.
- Results indicated that high altitude patients had larger lumen areas, less plaque burden, and significantly lower calcification percentages compared to their sea-level counterparts.
- These differences remained significant even after adjusting for clinical factors, suggesting that living at higher altitudes may affect the composition of carotid plaques.