Publications by authors named "Cantle F"
Article Synopsis
- - The study explored the feasibility of using high-flow humidified oxygen (HiFlo) as a treatment for children aged 2-11 with acute severe asthma (ASA) who did not respond to standard inhaled bronchodilator treatment.
- - In a randomized controlled trial involving 56 children, those receiving HiFlo experienced a lower treatment failure rate (64%) compared to the standard care group (86%), and they also had a faster time to meet hospital discharge criteria (29.3 hours vs. 36.8 hours).
- - The findings suggest that HiFlo could be a promising intervention for childhood ASA, warranting a larger definitive trial to evaluate its effectiveness despite the initial lack of evidence.
Article Synopsis
- Acute severe asthma (ASA) is a major reason children visit the hospital, with standard treatments often inadequate for some patients, highlighting the need for improved therapies like high-flow humidified oxygen (HiFlo).
- This study aims to determine if a full randomized controlled trial (RCT) on HiFlo therapy for ASA in children can be done effectively, evaluating recruitment methods and outcome measures.
- A feasibility RCT was conducted with children aged 2-11 not responding to standard care to assess HiFlo's impact on treatment failure rates and hospital discharge times, gathering patient and parent feedback for comprehensive evaluation.
Objectives: To evaluate a strategy designed to optimize care and increase uptake of urate-lowering therapy (ULT) during hospitalizations for gout flares.
Methods: We conducted a prospective cohort study to evaluate a strategy that combined optimal in-hospital gout management with a nurse-led, follow-up appointment, followed by handover to primary care. Outcomes, including ULT initiation, urate target attainment and re-hospitalization rates, were compared between patients hospitalized for flares in the 12 months post-implementation and a retrospective cohort of hospitalized patients from 12 months pre-implementation.
Background And Importance: Healthcare worker strikes are a global phenomenon. Mortality and morbidity seem to be unaffected by doctor strikes, but there is little evidence on the impact on emergency department (ED) flow and patient characteristics. In March and April 2023, two consecutive UK junior doctor strikes occurred.
View Article and Find Full Text PDFObjective: Synthetic cannabinoid receptor agonists (SCRA) are commonly encountered new psychoactive substances. Here we report the recent detection of ADB-BUTINACA in samples from patients attending United Kingdom emergency departments with toxicity after suspected drug misuse and describe the associated clinical features.
Methods: Consenting adults (≥16 y) presenting to participating hospitals with toxicity after suspected drug misuse have been included in the Identification Of Novel psychoActive substances (IONA) study since March 2015.
Background: Knife-related violence is of growing concern in the UK. This study aims to investigate the impact of the COVID-19 pandemic on the frequency of penetrating injuries at a UK major trauma centre.
Methods: This was a retrospective study comparing the number of patients attending the emergency department of King's College Hospital (KCH) with a penetrating injury (gunshot or stab wound) during the 'pandemic year' (1 March 2020-28 February 2021) compared with the equivalent time period in the previous year.
Article Synopsis
- The study investigated whether azithromycin could help reduce hospital admissions for patients with mild-to-moderate COVID-19, given its antibacterial and anti-inflammatory properties.
- Conducted in the UK with 298 participants, the trial randomly assigned patients to receive either azithromycin plus standard care or standard care alone.
- Results indicated that adding azithromycin did not significantly decrease the risk of hospital admission or death compared to standard care, with similar outcomes for both groups.
Comparison of presentations to the emergency department during the COVID-19 pandemic (COPED-C).
J Public Health (Oxf)
December 2021
Background: Concerns have been raised that patients requiring emergency care may not have accessed healthcare services during coronavirus disease 2019 (COVID-19) lockdown.
Methods: This case control study aimed to understand changes in characteristics and diagnosis of patients attending a large UK Emergency Department (ED) during the first wave of the COVID-19 pandemic (March-May 2020) compared with equivalent weeks in 2019.
Results: We found a 50.
Background: The COVID-19 pandemic continues to escalate. There is urgent need to stratify patients. Understanding risk of deterioration will assist in admission and discharge decisions, and help selection for clinical studies to indicate where risk of therapy-related complications is justified.
View Article and Find Full Text PDFWhat is a 'learning organization' in general practice? A case study.
Health Serv Manage Res
August 2000
The focus of the research herein was to examine the main characteristics of a learning organization in a general practice. An ethnographic approach was taken. Blockage instrument, structured interviews and documentary evidence were used to establish the validity and the reliability of the research.
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