Analysis of Macular Microvasculature in Human Immunodeficiency Virus Infection.

Purpose: To evaluate the retinal and choroidal microvascular blood flow in patients with human immunodeficiency virus (HIV) infection using optical coherence tomography angiography (OCTA).

Methods: Macular OCTA parameters including vessel density (VD) of parafoveal superficial capillary plexus (SCP-VD) and deep capillary plexus (DCP-VD), foveal vessel density (FD), foveal avascular zone area, and flow area of choriocapillaris were analyzed in 42 HIV-positive patients, and compared with 42 healthy controls.

Results: The mean SCP-VD, DCP-VD and FD were significantly lower in HIV-positive group compared with controls (p < .