Synopsis of recent research by authors named "Canrong Ni"
- Canrong Ni's recent research primarily focuses on the mechanisms underlying pancreatic tumorigenesis, particularly the roles of specific proteins and microRNAs, such as the PI3K/c-Myc/AFF4 axis and microRNAs like miR-194 and miR-192, in promoting cancer cell proliferation and malignant behavior.
- His studies have provided insights into the significance of nucleotide metabolism and lipid metabolism changes in cancer cells, emphasizing how these alterations can drive tumor development, especially in pancreatic ductal carcinoma (PDAC).
- Additionally, Ni has contributed to understanding the clinical aspects of pancreatic cancer surgeries, identifying risk factors for positive resection margins and evaluating the prognostic implications of tumor-stroma ratios in PDAC patients, thereby linking molecular findings with clinical outcomes.
