A retrospective study on the efficacy of short-term perioperative prophylaxis in abdominal surgery for hernia repair in 1,254 patients.

Between 1992 and 1999 1,254 patients requiring hernioplasty came to our Department of Surgery, at San Giovanni Valdarno Hospital, Arezzo. In 94% of cases a prosthetic device was inserted. All patients received a preoperative antibiotic prophylaxis with ceftriaxone, administered intravenously in a single 2 g dose, before surgery.

[The use of mesh in abdominal wall defects].

Today abdominal wall defect repair can't prescind from the use of prosthetic materials. Inguinal, femoral and incisional hernias represent more frequent events in which, only using prosthetic materials is it possible to perform "tension-free" repair. Prosthetic repairs "agree with" abdominal, wall physio-pathology, guarantee results and prevent recurrences.

[Jejunal mucosectomy as a preliminary technique of pancreatico-jejunal anastomosis].

The Authors describe mucosectomy as a preliminary technique to pancreatico-jejunal anastomosis. The removal of the last few centimeters of the jejunal mucosa enhances the perfect adhesion of the loop to the pancreatic parenchyma. Results seem to confirm theory: in our experience, "telescopic" technique associated with mucosectomy and somatostatin administration prevented so far anastomotic leakages.

[Sulglicotide in the treatment of dyspeptic patients with duodenogastric reflux].

The therapeutic efficacy of sulglicotide was tested in an open study of dyspeptic patients suffering from proven duodenogastric reflux. Twenty outpatients with non-ulcer dyspepsia and alkaline reflux demonstrated by measurement of enterogastric flux were enrolled in the study. All patients could be evaluated at the end of 8 weeks' treatment with 200 mg sulglicotide t.

[Personal experience in the area of colorectal anastomoses without protective colostomy].

The Authors report their past 3-year-experience in colorectal anastomosis without protective colostomy. General results in terms of complications and mortality rates are similar if not even better than those referred by the international Literature.

[Histopathology of reflux esophagitis at an early phase. Study and significance of intraepithelial eosinophilia].

The diagnosis of reflux esophagitis in the early stage is not easy because endoscopy rarely shows evident findings and histology of biopsy specimens still appears unclear and doubtful. Usual histopathological findings are reported and most available diagnostic criteria are discussed, on the basis of the literature and personal experience. Intraepithelial eosinophils are a possible marker of early reflux esophagitis: its diagnostic usefulness is outlined.

[Gastroesophageal reflux of mixed type].

Gastroesophageal reflux has been showed both clinically and experimentally to be especially damaging esophageal mucosal layer when the elements which make up reflux are gastric content and bilio-pancreatic juice.