Publications by authors named "Candy H Y Wong"
Article Synopsis
- This study examined how age-related cognitive decline varies internationally by analyzing data from 14 cohorts across 12 countries, totaling 42,170 individuals aged 54-105.
- Cognitive performance on tests like the Mini-Mental State Examination declined with age, with the fastest decline seen in processing speed at -0.26 standard deviations per decade.
- Results showed differences based on demographics, with Asian individuals experiencing a quicker decline compared to whites, and females declining faster than males on cognitive assessments.
Objective: This study investigated the potential of physical exercise habit as a lifestyle modification against cognitive and functional decline at the community level.
Methods: A total of 454 community-dwelling Chinese older adults without dementia participated in the Hong Kong Memory and Ageing Prospective Study at baseline and follow-up at 5 years. Their cognitive and functional performances were assessed by the Cantonese version of the Mini-Mental State Examination (CMMSE) and the Chinese version of Disability Assessment in Dementia (DAD).
Background: Changes in criteria and differences in populations studied and methodology have produced a wide range of prevalence estimates for mild cognitive impairment (MCI).
Methods: Uniform criteria were applied to harmonized data from 11 studies from USA, Europe, Asia and Australia, and MCI prevalence estimates determined using three separate definitions of cognitive impairment.
Results: The published range of MCI prevalence estimates was 5.
COSMIC (Cohort Studies of Memory in an International Consortium): an international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups.
BMC Neurol
November 2013
Background: A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and conditions like mild cognitive impairment and dementia have been inconsistent. Some of the problems confounding this research can be reduced by harmonising and pooling data across studies. COSMIC (Cohort Studies of Memory in an International Consortium) aims to harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders.
View Article and Find Full Text PDFBackground: This study evaluates which cognitive measure is best for predicting incident dementia in a population-based random sample of Chinese older adults without dementia over a five-year period.
Methods: A total of 787 community-dwelling Chinese older adults without dementia in Hong Kong were assessed at baseline (T0), at two years (T1), and at five years (T2).
Results: The annual conversion rate to dementia was 1.
Background: The clinical significance of subjective memory complaints in elderly subjects has been an area of active research. In this study, we evaluated subjective complaints and self-evaluation of memory test performance in subjects with Questionable dementia (QD) and mild Alzheimer's disease (AD).
Methods: Ninety-two subjects (35 cognitively intact normal controls NC, 33 QD, and 24 mild AD) were assessed.