Detection of acetone processing of castor bean mash for forensic investigation of ricin preparation methods.

Samples containing the toxic castor bean protein ricin have been recently seized in connection with biocriminal activity. Analytical methods that enable investigators to determine how the samples were prepared and to match seized samples to potential source materials are needed. One commonly described crude ricin preparation method is acetone extraction of crushed castor beans.

On the interpretation of test sensitivity in the two-test two-population problem: assumptions matter.

Bayesian analyses of diagnostic test accuracy often require the assumption of constant test accuracy among populations to ensure model identifiability. In a prior study (Toft, N., Jørgensen, E.