Salivary protein homology between humans and dogs: Mass spectrometry-based proteomics analysis.

Objective: This benchmark study aimed to investigate sex-related differences based on the identification and characterization of the salivary proteome of healthy male and female dogs using mass spectrometry (MS) technique and a homology-driven approach to analyze salivary proteins in both human and dog species utilizing protein sequence alignment technique.

Methods: Unstimulated whole saliva was collected from 10 healthy Beagles. After processing the samples and determining the total protein content, in-solution protein digestion was performed involving denaturation, reduction of disulfide bonds, alkylation, and removal of interfering compounds.

Computed tomography features of presumed normal mandibular and medial retropharyngeal lymph nodes in dogs.

Computed tomographic (CT) features of lymph nodes are used for diagnosis, staging, and response evaluation in veterinary patients. The objectives of this study were to describe maximum short- and long-axis transverse diameters (SATD and LATD, respectively), volume, and attenuation of presumed normal canine mandibular lymph nodes (MLNs) and medial retropharyngeal lymph nodes (MRLNs), to investigate the effect of variables on these features, and to describe inter-observer reliability of transverse diameter and attenuation measurement. Computed tomography studies of 161 dogs were retrospectively reviewed.

Pilot study of the effectiveness of a xylitol-based drinking water additive to reduce plaque and calculus accumulation in dogs.

Over a period of 208 days a randomized, double-blind clinical trial was conducted to assess plaque and calculus accumulation in dogs provided with a xylitol-based drinking water additive. A crossover design was utilized allowing each dog to participate in each 90-day treatment and control phase. Inclusion of a xylitol drinking water additive resulted in a 5.