Publications by authors named "Candace Glendening"
Article Synopsis
- The use of dry cow therapy (DCT), which involves intramammary antimicrobial drugs at the end of lactation, is common in US dairy farms and may impact the bacterial ecology.
- A study in Ohio, analyzing fecal samples from dairy cows, revealed that herds using cephalosporin-based DCT had more fecal coliform bacteria resistant to certain antimicrobials compared to those using penicillin/streptomycin therapy.
- While this indicates a potential influence on antimicrobial resistance among gut bacteria, the broader health implications for animals and humans remain uncertain.
Swine have been identified as the primary reservoir of pathogenic Yersinia enterocolitica (YE), but little research has focused on the epidemiology of YE at the farm level. The objective of this study was to describe the prevalence of YE in different production phases on swine farms. In this cross-sectional study, individual pigs on eight swine operations were sampled for the presence of YE.
View Article and Find Full Text PDFThe paramyxovirus template for transcription and genome replication consists of the RNA genome encapsidated by the nucleocapsid protein (N protein). The activity of the complex, consisting of viral polymerase plus template, can be measured with minireplicons in which the genomic coding sequence is replaced by chloramphenical acetyltransferase (CAT) antisense RNA. Using this approach, we showed that the C-terminal 24 amino acids of the measles virus N protein are dispensable for transcription and replication, based upon the truncation of N proteins used to support minireplicon reporter gene expression.
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