Atrial fibrillation (AF) recurrence after cardioversion is common, and inflammation plays a critical role in its pathophysiology. We aimed to elucidate the predictive role of the ratio of high-density lipoprotein cholesterol to c-reactive protein (HDL-C/CRP) as an inflammatory marker in AF recurrence after electrical cardioversion (ECV). We analyzed patients who underwent elective ECV for atrial fibrillation between June 2020 and December 2023.
View Article and Find Full Text PDFPatients who have been intubated ≥48 hours are at risk of dysphagia. Evaluation of swallowing before starting oral feeding after extubation is necessary to prevent aspiration and the problems caused by aspiration. The Postextubation Dysphagia Screening tool is a validated and reliable tool used to evaluate extubation-induced dysphagia.
View Article and Find Full Text PDFRib graft is a common source of cartilage in rhinoplasty. Donor site choices for this resource were identified according to the authors who presented the introduction of this technique. However, the scientific basis of this valuable method lacks information, including the anatomical properties of costal cartilage.
View Article and Find Full Text PDFBackground: YouTube has educational videos on inhalers. However, their content and quality are not adequately known.
Objectives: This study investigated the quality and content of educational YouTube videos on inhalers.
Aims And Objectives: This study aims to determine the relationship between perceptions of nursing presence and intensive care experiences in adult intensive care unit patients'.
Background: Intensive care units (ICUs) are settings where patients have many negative emotions and experiences, which affect both treatment and post-discharge outcomes. The holistic presence of nurses may help patients turn their negative emotions and experiences into positive ones.
Objectives: This study aimed to determine the Internet use, eHealth literacy levels, and influencing factors in Turkish cancer patients.
Data Sources: A descriptive and correlational study was conducted in a single cancer center with 296 patients. Data were collected using a personal information form, an Internet Usage Form, and the eHealth Literacy Scale (eHEALS).
Prim Care Diabetes
August 2023
Aims: The purpose of the study was to determine the relationship between family support and self-care in patients with type 2 diabetes in Middle Anatolia Region of Turkey.
Methods: This descriptive relation-seeker-type study conducted with 284 patients who met inclusion criteria between February and May 2020 in the internal medicine and endocrinology clinics and polyclinics of a university hospital. Data were collected using, a demographic questionnaire, Hensarling's Diabetes Family Support Scale (HDFSS), and Diabetes Self-Care Scale (DSCS).
Objectives: Older patients with cancer present many symptoms during treatment. One of those symptoms is fatigue, which may be caused by factors unrelated to cancer. One of those factors is frailty increased with age.
View Article and Find Full Text PDFPurpose: To report the clinicopathologic correlation and biochemical analysis of silicone oil removed after 23 years in an eye.
Methods: A 63-years-old man with a history of HIV/AIDS and cytomegalovirus retinitis, status post retinal detachment repair with silicone oil at the age of 39 years, presented with several weeks of worse vision. He was found to have a shallow fovea-off tractional retinal detachment.
Background: Glycemic control is crucial for reducing morbidity and mortality in critically ill patients. A standardized approach to glycemic control using a computer-guided protocol may help maintain blood glucose level within a target range and prevent human-induced medical errors.
Objective: To determine the effectiveness of a computer-guided glucose management protocol for glycemic control in intensive care patients.
1. A total of 420 male 1-d-old chicks of a slow-growing genetic line (Hubbard ISA Red JA) were used as the trial material. Two diets that were low in fats and high in cereals, and free from growth promoters and animal protein, and formulated at two energy and protein concentrations, were fed ad libitum or 80% of ad libitum.
View Article and Find Full Text PDFBackground: To investigate the possible effects of repeated sevoflurane and desflurane anesthesia on hepatocellular system by evaluating the free radical metabolism, hepatocellular enzymes and histopatholgical changes in rats.
Methods: Four groups of animals were studied. Sevoflurane 2% (v/v) and desflurane 6% (v/v) in air/O2 were administered to animals in group II (n=9) and III (n=9) respectively.
Aim: The effect of Diosmin Hesperidin on intestinal ischaemia reperfusion injury was evaluated in an experimental model in rats.
Material And Methods: Forty Spraque-Dawley rats were divided into 4 groups of (n = 10) (sham, sham + Diosmin Hesperidin, Reperfusion, Reperfusion + Diosmin Hesperidin). Diosmin Hesperidin oral gavage was administrated at a dose of 50 mg/kg to rats 14 and 2 hours before the operation and 30 minutes of ischaemia and 30 minutes of reperfusion was performed in the groups when appropriate.
Increased oxidative stress and impaired anti-oxidant defense have been suggested as contributory factors for initiation and progression of complications in diabetes mellitus. Aging itself has been shown to be along with increased oxidative stress and lower anti-oxidant defense. We aimed at investigating oxidative stress and anti-oxidant enzymes in 61 elderly subjects.
View Article and Find Full Text PDFBackground: The aim of the present study was to investigate the effect of N-acetylcysteine on intestinal reperfusion injury.
Methods: Forty Sprague-Dawley rats were divided into four groups (n = 10): sham, sham + N-acetylcysteine, reperfusion, and reperfusion + N-acetylcysteine. Thirty minutes of ischaemia +/- 30 min of reperfusion was performed under 100 mg/kg N-acetylcysteine or placebo, administered 30 min before the operation in the groups where appropriate.
The aim of the present study was to investigate the effects of treatment with antioxidant stobadine (ST) on the activities of enzymes related with pentose phosphate pathway and glutathione-dependent metabolism and the other markers of oxidative stress in brain and peripheral organs of diabetic rats, and to compare the effects of ST treatment alone with the effects of treatments with another antioxidant vitamin E and ST plus vitamin E. Rats were made diabetic by the injection of streptozotocin (STZ; 55 mg/kg IP), and, 2 days later, some control and diabetic rats were left untreated or treated with ST (24.7 mg/kg/day, orally), vitamin E (400-500 U/kg/day, orally), or both substances together.
View Article and Find Full Text PDFBecause elevated oxidative stress may exacerbate cardiovascular complications of diabetes mellitus, the current study aimed to investigate the effects of treatment with either vitamin A, an antioxidant, or with insulin on lipid peroxidation products and antioxidant enzyme activities of diabetic rat heart. Also to evaluate whether a combination of vitamin A and insulin exerts more beneficial effects than treatment with each agent alone. Rats were made diabetic with a single injection of streptozotocin (STZ, 55 mg kg(-1) i.
View Article and Find Full Text PDFThe present study investigated the effects of alpha-lipoic acid treatment (50 mg/kg/day) on the metabolism and vascular condition already damaged by streptozotocin (STZ)-diabetes in rats. Carbohydrate and lipid metabolism, oxidative stress and antioxidant status were assessed in non-diabetic controls, 12-week untreated diabetic and 12-week treated diabetic (untreated for 6 weeks and then treated with alpha-lipoic acid for the last 6 weeks) rats. Blood pressures of rats were measured by tail-cuff method.
View Article and Find Full Text PDFIn order to characterize human colorectal cancer, much attention has been paid to enzyme studies. However, little is known about the correlation between the levels of key enzymes of purine nucleotide pathway and some clinical and biological indicators of tumor invasiveness and aggressiveness. Adenosine deaminase (ADA) and 5'-nucleotidase (5'-NT) were measured in cancerous and cancer-free adjacent large bowel tissues from 38 patients with colorectal carcinoma.
View Article and Find Full Text PDFThree methods in the diagnosis and treatment of tuberculosis have been compared in this study. Serum adenosine deaminase activities of patients with tuberculosis was compared with those of control groups with (+) and (-) PPD (purified protein derivative) results and were found to be higher than the controls. Within the controls the PPD (+) group displayed higher adenosine deaminase activities in comparison to the PPD (-) group.
View Article and Find Full Text PDFErythropoietin (Epo) synthesis is suppressed in normoxia and stimulated in hypoxia. To test the hypothesis that the cellular H2O2 level is important in the control of Epo synthesis, we have studied effects of modulators of H2O2 generation and degradation on Epo production in human hepatic cell cultures (hepatoma lines HepG2 and Hep3B). In addition, we measured the activities of antioxidant enzymes (catalase, superoxide dismutase, glutathione peroxidase) in cultures following hypoxia exposure or H2O2 treatment.
View Article and Find Full Text PDFJ Clin Pharm Ther
February 2009
Objective: To study the possible effects of gentamicin on the enzymic free-radical defence system in the lung.
Method: Activities of cytoplasmic superoxide dismutase (CuZn-SOD), mitochondrial superoxide dismutase (Mn-SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) enzymes were studied in lung tissues from gentamicin-treated guinea-pigs compared to controls.
Results: Levels of those enzymes were higher in the gentamicin group except for xanthine oxidase (XO) activity.
Can J Anaesth
September 1997
Purpose: To investigate the effects of halothane and halothane plus vitamin E treatment on myocardial free radical metabolism in guinea pigs.
Methods: Four groups of seven animals were studied: control, halothane, halothane plus vitamin E and vitamin E groups. In the halothane group, halothane 1.