Preparation, structural characterization, and bioactivities of polysaccharides from Rhodiola: A review.

Rhodiola, the dried rhizome of various plants of the family Crassulaceae and genus Rhodiola, has been used as a traditional Tibetan medicine for thousands of years, with high medicinal and healthcare value. Polysaccharides, the major active components of Rhodiola, have attracted widespread attention due to their abundant biological activities and medicinal value. Rhodiola polysaccharides (RPs) have various biological activities such as germ cell protection, antioxidant, immunomodulatory, anti-fatigue, hypoglycemic, anti-tumor, and hematopoietic functions.

Study on the Molecular Mechanism of Baicalin Phosphorylation of Tau Protein Content in a Cell Model of Intervention Cognitive Impairment.

Objective: This study aimed to predict the molecular mechanism of baicalein through network pharmacology, cell experiments and molecular docking. The goal was to elucidate the mechanism for the treatment of mild cognitive impairment.

Materials And Methods: The protein-protein interaction network (PPI) and Cytoscape software were used to screen the hub genes of intersection genes, while the therapeutic mechanism of baicalein was predicted through the Gene ontology (GO) and Kyoto Encyclopedia of Gene and Genomes (KEGG) enrichment analysis.