Retrospective analysis of earthquake related crush injurie patients in ICU: 6-February earthquake in Türkiye.

Background: On February 6, 2023 a devastating earthquake hit the south-eastern region of Türkiye and thousands of people were either injured or died. The aim was to determine the characteristics, treatment and clinical outcomes of critically ill patients with crush injuries in ICU.

Subjects/methods: This study was performed with a retrospective design in ICU.

Refusal of the hospitalization: a distressed dilemma in obstetric practice.

Background: Pregnant women are a special population in which hospitalizations are more recommended due to physiological changes mimicking pathologies and medico-legal concerns.

Objectives: We aimed to assess the obstetric outcomes of expectant mothers who were admitted to the obstetrics emergency outpatient clinic and declined the hospitalization advised by doctors. Additionally, we examined the appropriateness of physicians' recommendations.

Impact of scoliosis on gestational outcome.

Objective: To demonstrate the impact of scoliosis on pregnancy and gestational outcome.

Material And Methods: We retrospectively evaluated gestational outcomes of pregnant women with scoliosis at Hacettepe University Hospital between 2008 and 2018. Cases were grouped according to the presence of previous scoliosis surgery and compared in terms of gestational week at birth, birthweight, rate of neonatal intensive care unit admission, hospitalization during pregnancy, route of delivery, type of anesthesia at labor and postpartum intensive care unit admission rate.

Presence of fetal DNA in maternal exhaled breath condensate.

Objectives: Cell-free DNA has been found in all body fluids, but DNAs emerging from locations that are not in direct contact with breath in exhaled breath condensate (EBC) are yet to be found. The potential of EBC for prenatal and cancer screening prompted us to investigate whether fetal DNA is present in maternal EBC.

Method: A total of 20 pregnant women's EBC and blood samples were collected.

The Effects of Systemic Coenzyme Q10 Treatment on Corneal Histology in Streptozocin-Induced Diabetic Rats.

Objective: This study investigate the histopathological changes and VEGF, IL-1β, and IL-6 immunoreactivities in cornea treated with Coenzyme Q10 (CoQ10) in a Streptozocin (STZ) induced diabetic rat model.

Methods: A total of 20 male Wistar Albino rats including a group of STZ diabetic rats, diabetic rats treated with CoQ10, rats were given CoQ10 without being diabetic and a Control group were included the study. The groups were followed up for 2 months.

Trimester-based changes in urogenital symptoms and their impact on the quality of life in pregnant women: A preliminary report.

Background: This study is aimed to determine the trimester-based changes in urogenital symptoms and their impact on the quality of life in pregnant women.

Materials And Methods: Fifty-one pregnant women participated in this study. Self-reported symptom-based questionnaires, Urogenital Distress Inventory-Short Form (UDI-6), Incontinence Severity Index (ISI), and Incontinence Impact Questionnaire (IIQ-7) were administered to determine urogenital symptoms, incontinence severity, and the quality of life in all participants in the first, second, and third trimesters.

Gestational Outcomes of Pregnant Women with Unilateral Congenital Renal Agenesis.

We evaluated if there were more adverse gestational outcomes of pregnant women with unilateral congenital renal agenesis (UCRA). This single center retrospective case-control study compared maternal complications and neonatal outcomes from 25 women with UCRA to the outcomes of 125 women with two kidneys. UCRA women had lower gestational weeks at birth and higher rates of preterm delivery ( = 0.

Effect of anti-epileptic drugs on first trimester screening test results.

Objective: To evaluate first trimester screening test parameters in epileptic patients using anti-epileptic drugs.

Materials And Methods: We retrospectively evaluated first trimester screening test results of 23 epileptic pregnant women using anti-epileptic drugs with a control group consisting of 92 healthy pregnancies. The anti-epileptic drugs used in this study were carbamazepine, levatiracetam, valproic acid and lamotrigine.

Maternal Mortality: 10 Year Experience of a Tertiary Center in Turkey.

We retrospectively evaluated five maternal mortality cases that occurred in our institution within the last 10 years. Rate of maternal mortality was 24.5 per 100000 live births.

The Effect of Asthma Severity on Perinatal Outcomes: A Tertiary Hospital Experience.

Objective: To evaluate the effect of asthma severity and disease exacerbation on pregnancy outcomes.

Materials And Methods: Pregnancies were classified into 3 groups as mild (n=195), moderate (n=63), and severe (n=26) according to preconceptional asthma severity. Demographic features, clinical characteristics, and perinatal outcomes were compared between the groups.

Assessment of Factors Affecting Breastfeeding Performance and Latch Score: A Prospective Cohort Study.

Objective: To determine the risk factors that may affect LATCH scores.

Materials And Methods: We prospectively evaluated the LATCH scores and any relevant risk factors of patients who delivered at our institution during April and May 2020. All examinations were performed by the same physicians during the study period.

The Effect of Small Size Uterine Fibroids on Pregnancy Outcomes in High-risk Pregnancies.

Objective:  To evaluate the obstetric outcomes of singleton high-risk pregnancies with a small size uterine fibroid.

Methods:  This retrospective cohort study was conducted among 172 high-risk pregnant women who were followed-up by a single surgeon between 2016 and 2019. Pregnant women with preconceptionally diagnosed small size (< 5 cm) single uterine fibroids ( = 25) were compared with pregnant women without uterine fibroids ( = 147) in terms of obstetric outcomes.

Acrochordons and autoimmunity: Significance of preconceptional counseling.

Background: Acrochordons are benign hypertrophic lesions of the skin of which the pathophysiology is unclear.

Objective: This study aimed to examine the association of acrochordons with autoimmune disorders in patients with a poor obstetric history.

Methods: This retrospective cohort involved 350 female patients with poor obstetric history who were included in a preconceptional care program to investigate risk factors for obstetric complications.

Importance of shock index in the evaluation of postpartum hemorrhage cases that necessitate blood transfusion.

This study aims to determine cutoff values for shock index (SI) to predict the need for transfusion and composite adverse outcomes in postpartum hemorrhage (PPH) cases. One hundred thirty PPH cases (study group) that necessitated blood transfusion were retrospectively compared to a frequency-matched control group (n = 130). Receiver operating characteristic (ROC) curves and decision tree [Classification & Regression Tree (C&RT) and Chi-square Automatic Interaction Detector (CHAID)] were used to identify cutoff values for SI.

Granulomatosis with polyangiitis and pregnancy: Anti-neutrophil cytoplasmic antibody, placental inflammation, chorangiosis and pre-eclampsia.

Granulomatosis with polyangiitis (GPA) is a rare necrotizing autoimmune disease involving small vessel vasculitis. Pregnancies with GPA have increased rates of obstetric complications including pre-eclampsia. Differential diagnosis of GPA flares up and pre-eclampsia may be difficult and necessitates careful clinical practice.

A cut-off value for systemic immune-inflammation index in the prediction of adverse neonatal outcomes in preterm premature rupture of the membranes.

Aim: To determine a cut-off value for systemic immune-inflammation index (SII)(neutrophil × platelet /lymphocyte) in the prediction of adverse neonatal outcomes in preterm premature rupture of the membranes (PPROM).

Methods: This retrospective cohort study was conducted among singleton pregnancies with PPROM. Cases were divided into two main groups: Group 1) PPROM diagnosed at 24th-28th weeks of gestation and Group 2) PPROM diagnosed at >28th-34th weeks of gestation.

Prenatal diagnosis of central nervous system abnormalities: Neurosonography versus fetal magnetic resonance imaging.

Objective: To share our experience in diagnosis of congenital central nervous system (CNS) abnormalities by fetal magnetic resonance imaging (MRI).

Study Design: This study consisted of 110 pregnancies. Neurosonography (NS) findings were compared with MRI results.

Is bacterial vaginosis associated with autoimmune antibody positivity?

Objective: To evaluate the association between bacterial vaginosis (BV) and autoimmune antibody positivity.

Method: We evaluated Papanicolaou-stained cervicovaginal smears of 210 patients with poor obstetric history who were admitted to a special preconception counselling programme. Cytological specimens with various types of microorganisms except for BV, epithelial cell abnormalities and other non-neoplastic findings, including inflammation were excluded from the cohort in addition to patients with autoimmune and chronic inflammatory diseases.

Relationship of Cholelithiasis and Urolithiasis with Methylenetetrahydrofolate Reductase Polymorphisms.

Aim: To investigate the relationship of cholelithiasis and urolithiasis with (MTHFR) polymorphism(s) in patients with poor obstetric history to search whether they are risk factors for adverse pregnancy outcome.

Materials And Method: This study is consisted of 94 patients with poor obstetric history. Patients were evaluated in terms of the presence of cholelithiasis and urolithiasis in association with MTHFR polymorphism(s).

Comparison of term and preterm labor procalcitonin and leukocyte cell volume, conductivity and light scatter (VCS) parameters in order to demonstrate the impact of inflammation on the triggering mechanisms of preterm uterin contractions.

Aim: Comparison of mean channels of cell volume, conductivity and light scatter (VCS) parameters of neutrophil, monocyte and lymphocyte, procalcitonin (PCT) and white blood cell count (WBC) during term and preterm labor to evaluate the impact of inflammation on the triggering mechanisms of uterine contractions.

Methods: This study is consisted of 16 preterm and 60 term pregnancies at the beginning of the first stages of the labor. Leukocyte VCS parameters, PCT plasma levels and WBC count were evaluated.

Effect of hypocomplementemia on perinatal outcomes of pregnancies with autoimmune disorders.

Objective: To demonstrate the effect of preconceptional complement levels on perinatal outcomes of pregnancies with autoimmune disorders.

Methods: Pregnant women with autoimmune disorders (autoimmune disease and/or autoimmune antibody positivity) who were screened for complement levels (C3 and C4) prior to their pregnancies were enrolled in a special antenatal care program. These patients were administered low-dose low-molecular-weight heparin (enoxaparine, 1 × 2000 Anti-XA IU/0.

5 Years' Experience of a Tertiary Center with Thrombocytopenic Pregnancies: Gestational Thrombocytopenia, Idiopathic Thrombocytopenic Purpura and Hypertensive Disorders of Pregnancy.

To evaluate thrombocytopenic pregnancies including gestational thrombocytopenia (GT), idiopathic thrombocytopenic purpura (ITP), and hypertensive disorders of pregnancy (HDP). We evaluated the pregnancy outcomes and laboratory findings of 385 patients diagnosed with GT, ITP, or HDP whose thrombocyte levels were < 150 000/µL. GT, ITP, and HDP were the final diagnoses in 315 (81.

5-year experience of a tertiary center in major congenital abnormalities in singleton pregnancies.

Objective: To demonstrate major congenital abnormalities delivered or terminated at our institution between 2014 and 2018.

Materials And Methods: Necessary information was retrieved from the registries of the delivery room and electronic database of Hacettepe University Hospital, Ankara.

Results: This study was consisted of 307 major congenital anomalies.

Chorionic villus sampling experience of a reference perinatal medicine center.

Aim: To share the chorionic villus sampling (CVS) experience of a single surgeon in our institution.

Methods: This retrospective study consists of CVS cases performed between 2000 and 2018. A total of 66 types of indications were classified under two main categories, the screening group (SG) and the inherited disease group (IDG).