Development of Interleukin-2 Loaded Chitosan-Based Nanogels Using Artificial Neural Networks and Investigating the Effects on Wound Healing in Rats.

The aim of this study was to develop and characterize rh- IL-2 loaded chitosan-based nanogels for the healing of wound incision in rats. Nanogels were prepared using chitosan and bovine serum albumin (BSA) by ionic gelation method and high temperature application, respectively. Particle size, zeta potential, and polydispersity index were measured for characterization of nanogels.

Clinicopathological consistency in skin disorders: a retrospective study of 3949 pathological reports.

Background: Although the clinicopathological approach plays an important role in skin disorder diagnoses, few studies have evaluated the consistency between clinical and histopathological diagnoses of skin disorders.

Objective: We sought to investigate the consistency, and factors affecting consistency, between clinical diagnoses and pathological diagnoses in patients with skin disorders referred for biopsy by dermatologists.

Methods: We retrospectively examined 3949 pathological reports of biopsy specimens, between 1999 and 2008.

Chlamydia, Mycoplasma and Ureaplasma infections in infertile couples and effects of these infections on fertility.

Objective: In our study, we aimed to determine the prevalence of Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum infections among infertile couples and effects of these infections on infertility.

Materials And Methods: Prevalence of Chlamydia, Mycoplasma, Ureaplasma antibodies and Chlamydia IgM antibodies and its effect on these agents' sperm parameters, namely, morphology, density, and motility were investigated among a total of 212 patients including fertile and infertile couples. Chlamydia, Mycoplasma, Ureaplasma antigens were evaluated using ELISA in the cervical and urethral samples.

Successful treatment of auricular pseudocyst with clothing button bolsters alone.

Abstract Auricular pseudocyst is clinically characterized by asymptomatic, non-inflammatory benign cystic swelling, usually located on the anterior or posterior helix. Recurrences have been observed frequently after simple drainage or aspiration of the lesions. Certain treatment modalities for the condition have been reported with variable success, complications and cosmetic results.

Human papilloma virus persistence and neopterin, folate and homocysteine levels in cervical dysplasias.

Objective: To investigate the relationship between human papilloma virus (HPV) infection persistence and serum folate, vitamin B12, homocysteine, neopterin levels in cervical dysplasia.

Study Design: Through the years 2007-2008, 122 women who have admitted to Gynecology Clinic were evaluated for cervical cytology, demographical characteristics, HPV infection, serum folate, vitamin B12, homocysteine, albumin, and neopterin levels.

Results: Considering all the cases, the highest percentage of the HPV-infected patients was in high-grade squamous intraepithelial lesion (HSIL) group (83%, n = 25).

Neurofibroma like nodules on shoulder: First sign of gastric adenocarcinoma.

Cutaneous metastasis is a relatively uncommon manifestation of visceral malignancies. It most often occurs late in the course of a disease but may also be the first presenting sign of advanced visceral cancer. The average incidence of cutaneous metastasis from a visceral neoplasm is 5.

Ross syndrome: Unilateral hyperhidrosis, Adie's tonic pupils and diffuse areflexia.

Ross syndrome is a rare disorder first described in 1958 with partial autonomic dysfunction. It has three basic components including unilateral or bilateral segmental anhidrosis, Adie's tonic pupils and areflexia or hyporeflexia of deep tendon reflexes. The most disturbing symptom in the patients is segmental compensatory hyperhidrosis and often the hypohidrosis or anhidrosis is not even noticed.

Treatment of focal epithelial hyperplasia with topical imiquimod: report of three cases.

Focal epithelial hyperplasia (Heck disease) is a rare disorder caused by specific types of HPV. It mainly involves oral mucosa and children are affected more frequently. It may persist for years, producing a significant reduction in quality of life.

Iododerma following sitz bath with povidone-iodine.

A 50-year-old man developed numerous pustules and bullae on the trunk and limbs 15 days after anal fissure surgery. The clinicopathological diagnosis was iododerma induced by topical povidone-iodine sitz baths postoperatively. Complete resolution occurred within 3 weeks using systemic corticosteroids and forced diuresis.