Paucigranulocytic asthma: Do sputum macrophages matter?

Although paucigranulocytic asthma (PGA) is the most common phenotype of stable asthma, its features have not been adequately studied. In this study, we aimed to display the characteristics of PGA. A total of 116 non-smoking adult patients with asthma (80% women; mean ± standard deviation age, 39 ± 12.

Primary Closure of Oroantral Communication Using Pedicled Buccal Fat Pad Following Maxillary Cyst Enucleation.

Odontogenic keratocyst (OKC) is a clinically aggressive developmental odontogenic cyst with a high recurrence rate as 62%. Oroantral communication (OAC) is a gateway through the maxillary sinus and the oral cavity, which, if not treated, will develop into oroantral fistula or chronical sinus diseases. Different methods for closure of OAC were described but only few of them have common usage.

The effects of supplemental melatonin administration on the healing of bone defects in streptozotocin-induced diabetic rats.

Objective: The aim of this study was to investigate histologic and biochemical effects of supplemental melatonin administration on bone healing and antioxidant defense mechanism in diabetic rats.

Material And Methods: Eighty-six Sprague-Dawley male rats were used in this study. Diabetes mellitus was induced by intraperitoneal (i.

Odontogenic lesions in a pediatric population: Review of the literature and presentation of 745 cases.

Objectives: Pediatric odontogenic lesions are rare clinical entities and are not well addressed in the otolaryngology literature. Knowledge of the biologic and clinical behavior of these lesions and their basic features such as location and age are key aspects for otolaryngologists in developing an early clinical differential diagnosis, such that they can provide adequate treatment.

Methods: Six thousand histologically-diagnosed odontogenic lesions from a 40-year period were reviewed.

Odontogenic and nonodontogenic cysts in Istanbul: analysis of 5088 cases.

Background: The aim of this study was to determine the prevalence of 5088 odontogenic and nonodontogenic cysts over a 40-year period in the Turkish population and to compare results with findings in the literature.

Methods: The records of odontogenic and nonodontogenic cysts, occurring during 1971 to 2010, were collected and analyzed for anatomic site, age range, and sex distribution.

Results: Among 5088 odontogenic and nonodontogenic cyst biopsies, 5003 cases (98.

Clinical and histopathological investigation of odontomas: review of the literature and presentation of 160 cases.

Purpose: The purpose of the present study was to evaluate the clinical and histopathologic aspects of different types of odontomas.

Materials And Methods: One hundred sixty odontoma cases sent to the Institute of Oncology, Department of Tumor Pathology, Istanbul University from 1971 through 2010 were investigated. These tumors were compared by age of patient, gender of patient, localization, histopathologic type, clinical diagnosis, and clinical and microscopic features.

P53 overexpression in nasopharyngeal carcinoma.

Nasopharyngeal carcinoma (NPC) is a characteristic tumor displaying epidemiological, genetic and regional distribution properties and is unique by its natural behavior and therapy. Investigation of the molecular and biological changes, gene amplifications and activations that occur during carcinogenesis and progression can provide new insight into the pathology of the disease and may add biological factors that can be used as new prognostic markers. The p53 tumor suppressor gene is the most frequently mutated gene in human cancer.