Publications by authors named "Can Barıs Aker"
Primary immune deficiencies are a group of heterogenous genetic disorders characterized by frequent infections, autoimmunity and malignancy. In this study, we aimed to evaluate clinical characteristics, outcomes of children with malignancy developed on background of primary immunodeficiency and compare survival rates of patients between malignant lymphoma with primary immunodeficiency and without immunodeficiency from tertiary oncology center in a developing country. A total 23 patients with primary immunodeficiency and malignancy were evaluated retrospectively.
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- Anthracyclines, commonly used for treating acute lymphoblastic leukemia (ALL), can cause cardiotoxicity, which may not show symptoms until years after initial exposure, raising the need for careful monitoring.
- The study examined 13 children with newly diagnosed ALL using advanced echocardiographic techniques to assess heart function before and after chemotherapy sessions.
- Results indicated that early signs of cardiotoxicity appeared during initial treatment phases, suggesting the importance of utilizing advanced imaging methods to detect and address heart damage sooner in pediatric ALL patients.*