Publications by authors named "Camryn Smith"
Background: The prevalence of sepsis and delirium in the elderly is a risk factor for subsequent diagnosis of Alzheimer's disease and related dementias (ADRD). Post-sepsis impairments include changes in memory, attention, emotional function, and neuromuscular strength. Studies have shown a link between the prolonged activation of microglia after infection.
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- - Delirium is a serious mental state disturbance seen in hospital patients, affecting attention, memory, and perception, and occurs in 18% to 25% of inpatients, especially during critical illnesses.
- - Neuroimaging techniques reveal brain changes—like atrophy and disrupted blood flow—while EEG studies show abnormal brain activity patterns related to delirium.
- - Understanding the role of inflammation and metabolic processes, along with animal models that simulate delirium, can help identify how it develops and lead to new treatment strategies.