Publications by authors named "Camron M Rivera"
Article Synopsis
- - The objective of the study was to analyze clear cell sarcoma (CCS) in relation to two other rare tumors: clear cell odontogenic carcinoma (CCOC) and clear cell carcinoma of the salivary gland (CCC) to find similarities among them.
- - The research involved reviewing existing literature, collecting data on the characteristics, symptoms, imaging results, and genetic features of these tumors through PubMed.
- - Findings indicated that CCS shares histological similarities and genetic profiles with CCOC and CCC, with all three tumors showing a tendency to occur in soft tissue and bones, primarily affecting women and typically presenting at different ages.
Detection of EWSR1 fusions in CCOC by targeted RNA-seq.
Oral Surg Oral Med Oral Pathol Oral Radiol
August 2022
Objective: To describe the application of a targeted RNA sequencing assay to detect fusion transcripts in formalin-fixed paraffin-embedded (FFPE), non-decalcified samples of clear cell odontogenic carcinoma (CCOC) and related tumors, and to add to knowledge of the genetic drivers of CCOC.
Study Design: Five FFPE tissues, including intraosseous CCOC (n = 3), clear cell carcinoma of the salivary gland (CCC, n = 1), and Ewing sarcoma (ES, n = 1), were analyzed by targeted RNA-seq to detect fusions.
Results: The 3 intraosseous CCOC samples harbored EWSR1 translocations: EWSR1-ATF1 (n = 2) and EWSR1-CREM (n = 1); the CCC sample contained an EWSR1-ATF1 fusion; and the ES sample contained an EWSR1-FLI1 fusion detected by RNA-seq.