To investigate the prevalence and clinical spectrum of atypical or non-classical complications in adult-onset Still's disease (AOSD) beyond macrophage activation syndrome (MAS) and to identify factors linked to their occurrence. Multicenter cross-sectional study of AODS cases included in the Spanish registry on Still's disease. This study included 107 patients (67% women), of whom 64 (59.
View Article and Find Full Text PDFObjective: To conduct a systematic review and meta-analysis to verify the association of aspects of sports practice with health risk behaviors in adolescents.
Data Source: A systematic search was conducted of electronic manuscripts from the United States National Library of Medicine (PubMed)/ Medical Literature Analysis and Retrieval System Online (MEDLINE), Web of Science, Science Direct, and Scientific Electronic Library Online (SciELO) published from January 2015 to December 2022. Studies examining the association between sport and health risk behaviors in adolescents aged 11 to 19 years were included.
Urban parks and cemeteries constitute hot spots of bird diversity in urban areas. However, the seasonal dynamics of their bird communities have been scarcely explored at large scales. This study aims to analyze the drivers of urban bird assemblage seasonality in urban parks and cemeteries comparing assemblages during breeding and non-breeding seasons in the Neotropical Region.
View Article and Find Full Text PDFSubcutaneous (SAT) and visceral (VAT) adipose tissue dysfunction during the obesity onset can lead to increased expression of inflammatory molecules, and consequently to immune cell infiltration. The aim was to deeply characterize the T cells, those infiltrating SAT and VAT, compared to peripheral blood (PB), in individuals undergoing bariatric surgery. Forty-two adult individuals were recruited, SAT and VAT samples were collected.
View Article and Find Full Text PDFNitrogen contamination of water sources poses significant environmental and health risks. The sulfur-driven simultaneous nitrification and autotrophic denitrification (SNAD) process offers a cost-effective solution, as it operates in a single reactor, requires no organic carbon addition, and produces minimal sludge. However, this process remains underexplored, with microbial population dynamics, their interactions, and their implications for process efficiency not yet fully understood.
View Article and Find Full Text PDFAims: Hypoalbuminemia is frequently found in patients with heart failure (HF), associated with higher morbimortality in acute HF (AHF). Moreover, Carbohydrate Antigen 125 (CA125) is elevated in most of the AHF patients. In this cohort of patients admitted for AHF, our objective was to evaluate the association between hypoalbuminemia and long-term outcomes, including mortality and HF readmissions, stratified by CA125 concentration.
View Article and Find Full Text PDFIntroduction: The COVID-19 pandemic changed the daily lives of university students and affected their mental health. The aim of this study was to assess the feelings and perceptions regarding the pandemic and teaching, and to identify the mental health symptoms perceived by pharmaceutical sciences students at a Brazilian public university.
Methods: This is a cross-sectional study with data triangulation (mixed-methods approach), conducted online with semiannual data collection from May 2020 to May 2021.
Bimetallic complexes have demonstrated a great ability to enhance the activity of monometallic systems for bond activation and catalysis. In this work, we explore the opposite approach: using a second metal to passivate the activity of another by reversible bimetallic inhibition. To do so we have synthesized a family of nine electrophilic gold complexes of formula Au(PR)(NTf) ([NTf] = [N(SOCF)]) that can act as inhibitors in the semihydrogenation of terminal and internal alkynes catalyzed by the iconic iridium Vaska complex IrCl(CO)(PPh).
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
December 2024
[This corrects the article DOI: 10.3389/fendo.2024.
View Article and Find Full Text PDF[(L1)Au(μ-H)MCp][BF] complexes (M = Mo and W) featuring cavity-shaped tris-2-(4,4'-di--butylbi-phenylyl)phosphine (L1) have been isolated. The tungsten derivative showed a remarkably fast reactivity in photolytic hydride transfer to generate the mononuclear gold hydride (L1)AuH. Both bimetallic adducts trap Ag cations, forming unprecedented {Au(μ-H)M(μ-H)Ag} trimetallic assemblies with destabilized Au-M interactions.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
January 2025
Camouflage is often considered a daytime phenomenon based on light and shade. Nocturnal camouflage can also occur, but its mechanistic basis remains unclear. Here, we analyze the conditions for background matching (BM) of avian predators against the night sky.
View Article and Find Full Text PDFImage-based spatial transcriptomics platforms are powerful tools often used to identify cell populations and describe gene expression in intact tissue. Spatial experiments return large, high-dimension datasets and several open-source software packages are available to facilitate analysis and visualization. Spatial results are typically imperfect.
View Article and Find Full Text PDFIntroduction: Recent literature continues to demonstrate the successful role of large-bore aspiration catheters in thrombus ingestion during mechanical thrombectomy. However catheter-to-microwire step-off and distal navigation are ongoing challenges in thrombectomy. A new to market 0.
View Article and Find Full Text PDFIn recent years, different laboratories have provided evidence on the role of miRNAs in regulation of corneal epithelial metabolism, permeability and wound healing, as well as their alteration after surgery and in some ocular pathologies. We searched the available databases reporting miRNA expression in the human eye, looking for miRNAs highly expressed in central cornea, which could be crucial for maintenance of the epithelial phenotype. Using the rabbit RCE1(5T5) cell line as a model of corneal epithelial differentiation, we describe the participation of miR-141-3p as a possible negative regulator of the proliferative/migratory phenotype in corneal epithelial cells.
View Article and Find Full Text PDFClimate and land-use changes are contributing to impacts on global ecosystem functioning. These effects are particularly severe in areas undergoing land abandonment and extreme wildfire events, such as the Mediterranean regions of the Iberian Peninsula. Previous studies have evaluated the impacts of land management on fire mitigation and biodiversity (species distribution and species richness), but how such strategies influence functional diversity remains unexplored.
View Article and Find Full Text PDFThe family of individuals living with Down Syndrome (DS) often demonstrate high levels of stress associated with the demand for care and difficulties experienced in everyday life. The aim of this cross-sectional study was to assess perceived stress by parents/caregivers of individuals with DS and its association with general perceived self-efficacy and dental outcomes, considering the COVID-19 pandemic's impacts on family's daily activities and finances. A sample of 257 parents/caregivers answered a questionnaire with socioeconomic, dental, and behavioral variables and the short version of the Perceived Stress Scale and the General Perceived Self-Efficacy Scale.
View Article and Find Full Text PDFAge-related hearing loss is a risk factor for mobility problems and falls, possibly due to poor access to spatial sounds or the higher allocation of attention required to listen, thereby reducing cognitive resources to support mobility. Introducing stabilizing spatial sounds or reducing cognitive load through hearing aids could possibly improve balance performance; however, evidence is mixed. Few studies have evaluated the effects of hearing aids and spatial sounds on balance during realistic, multisensory, dual-tasking conditions.
View Article and Find Full Text PDFIn the face of intense urban expansion, the assessment of water quality plays a crucial role in environmental preservation. Here, we evaluated aquatic genotoxicity in three locations with different degrees of urbanization using Tradescantia pallida var. purpurea and Daphnia magna as bioindicators.
View Article and Find Full Text PDFBackground: Over the past few decades, the scientific community has recognized the impact of physical activity on health and performance. In parallel, researchers have been actively exploring novel methodologies to analyze the physiological and metabolic responses to exercise. Fourier transform infrared spectroscopy has emerged as a powerful tool in this effort, offering the potential to provide unique insights into exercise-related changes at the molecular level.
View Article and Find Full Text PDFHungary relies heavily on fossil and nuclear fuel imports from Russia. An urgent challenge is to develop a more sustainable and more independent energy system. There is a 2019 and a 2023 (draft) version of the National Energy and Climate Plan (NECP) but they arguably do not follow this direction.
View Article and Find Full Text PDFVet Comp Orthop Traumatol
November 2024
Objective: To assess the biomechanical parameters of intact tibiotarsi (INT) and tibiotarsi with a 5-mm segmental diaphyseal defect repaired using four osteosynthesis techniques: a locking plate (LP), a plate-rod combination, an external skeletal fixator (one end-threaded positive-profile pin per fragment) with an intramedullary pin tie-in (TIF 1), and an external skeletal fixator (two end-threaded positive-profile pins per fragment) with an intramedullary pin tie-in (TIF 2).
Study Design: Sixty tibiotarsi from 30 adult laying hens were allocated into five groups for nondestructive dynamic torsion and four-point bending tests, followed by failure tests. Nondestructive dynamic tests evaluated stiffness over time in torsion and bending.