Publications by authors named "Camporotondo R"
Article Synopsis
- The study aimed to identify echocardiographic indicators that could predict the success of weaning patients from veno-arterial extracorporeal membrane oxygenation (V-A ECMO) and their survival after the procedure.
- It involved 76 patients undergoing V-A ECMO due to cardiogenic shock, measuring various echocardiographic parameters before and during the weaning process.
- Key findings highlighted that parameters like total isovolumic time (t-IVT), mitral annular plane systolic excursion (MAPSE), and left ventricular output velocity-time integral (LVOT VTI) were strong predictors of successful weaning and survival, whereas the left ventricular ejection fraction (LVEF) was not a reliable
Aims: To describe the use and the relation to outcome of different ventilation strategies in a contemporary, large, prospective registry of cardiogenic shock patients.
Methods And Results: Among 657 patients enrolled from March 2020 to November 2023, 198 (30.1%) received oxygen therapy (OT), 96 (14.
Article Synopsis
- Advanced heart failure (AdvHF) presents treatment difficulties, especially when options like mechanical support or transplants are not available, emphasizing a lack of solid medical management evidence.
- A study of 406 AdvHF patients receiving nightly sodium nitroprusside (SNP) infusions revealed no significant hypotension-related discontinuation, and a notable increase in blood pressure was observed after treatment.
- While the combination of SNP and dobutamine led to more weight loss, it also caused a higher rise in creatinine levels, suggesting a balance between effectiveness in improving patient outcomes and potential side effects.
Mortality for cardiogenic shock is still high despite optimal pharmacological therapy. Therefore, active mechanical circulatory support devices are increasingly used; venoarterial extracorporeal membrane oxygenation (VA-ECMO) enables full circulatory and respiratory support. However, recent data show that in patients with infarct-related shock unselected early use of VA-ECMO does not improve survival and is associated with major bleeding and peripheral ischemic complications.
View Article and Find Full Text PDFBackground: Antithrombotic therapy in acute patients with both high ischaemic and bleeding risks remains challenging.
Case Summary: We presented a challenging case involving a 48-year-old man referred to our hospital for headache and a left superior quadrantanopia. A CT scan revealed a right inferior occipital lobe ischaemic stroke.
Article Synopsis
- New guidelines say doctors shouldn't use a special heart pump called the IABP as much for patients with a certain kind of heart problem, but many still do.
- A study looked at almost 3,000 patients with severe heart issues to see if using the IABP helped them survive.
- Results showed that the IABP helped patients with anterior heart attacks live longer, but didn't really help others with different types of heart problems.
Article Synopsis
- The analysis from the Altshock-2 registry aimed to compare the clinical features and management of cardiogenic shock due to acutely decompensated heart failure (ADHF-CS) versus that caused by acute myocardial infarction (AMI-CS).
- It found that patients with ADHF-CS were younger but had worse kidney and liver function, leading to longer hospital stays and increased use of heart replacement therapies.
- In terms of treatment, norepinephrine was more common for AMI-CS, while epinephrine was more frequently used for ADHF-CS, and overall in-hospital mortality rates were similar between the two groups.
Background: Left ventricular (LV) remodelling (REM) ensuing after ST-elevation myocardial infarction (STEMI), has typically been studied by echocardiography, which has limitations, or cardiac magnetic resonance (CMR) in early phase that may overestimate infarct size (IS) due to tissue edema and stunning. This prospective, multicenter study investigated LV-REM performing CMR in the subacute phase, and 6 months after STEMI.
Methods And Results: patients with first STEMI undergoing successful primary angioplasty were consecutively enrolled.
Article Synopsis
- * Methods and Results: The study involved six CS patients on veno-arterial extracorporeal membrane oxygenation (VA-ECMO) who received ivabradine, compared to a similar group without the drug. Key health indicators, including heart rate and heart function, were monitored, revealing a significant heart rate drop and improved heart performance following ivabradine administration.
- * Conclusion: Ivabradine effectively lowered heart rate in CS patients
Background: Several risk factors have been identified to predict worse outcomes in patients affected by SARS-CoV-2 infection. Machine learning algorithms represent a novel approach to identifying a prediction model with a good discriminatory capacity to be easily used in clinical practice. The aim of this study was to obtain a risk score for in-hospital mortality in patients with coronavirus disease infection (COVID-19) based on a limited number of features collected at hospital admission.
View Article and Find Full Text PDFIntroduction: The role of sex compared to comorbidities and other prognostic variables in patients with coronavirus disease (COVID-19) is unclear.
Methods: This is a retrospective observational study on patients with COVID-19 infection, referred to 13 cardiology units. The primary objective was to assess the difference in risk of death between the sexes.
Article Synopsis
- * A total of 341 patients were analyzed, with findings indicating that patients with elevated levels of both NPs and troponin had a significantly higher risk of death, even when adjusted for other health factors.
- * The results suggest that NPs can help identify patients at risk of poor outcomes, even in those with normal troponin levels, highlighting their potential as a useful biomarker in COVID-19 prognosis.
Many ST-segment elevation acute coronary syndrome (STEACS) patients fail to activate the Emergency Medical System (EMS), with possible dramatic consequences. Prior studies focusing on barriers to EMS activation included patients with any acute coronary syndrome (ACS) without representation of southern European populations. We aimed to investigate the barriers to EMS call for patients diagnosed for STEACS in Italy.
View Article and Find Full Text PDFBackground: Acute kidney injury (AKI) is a well-known complication of ST-elevation acute myocardial infarction (STEMI) with an adverse impact on prognosis. Since AKI develops more frequently in elderly patients, we hypothesized that its higher incidence in older STEMI patients might explain their increased in-hospital mortality. We assessed the relationship between AKI and in-hospital mortality in patients with STEMI of different age groups.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on hospitalized COVID-19 patients to evaluate the impact of a history of atrial fibrillation (AF) on their clinical outcomes.
- Among the 696 patients, those with a history of AF had significantly higher mortality rates (38.7% vs 20.8%) and faced more in-hospital complications like new-onset AF and acute heart failure.
- Even after adjusting for other serious health factors, the presence of AF remained a critical risk factor for worse outcomes in these patients.
Aims: Myocardial injury (MI) in coronavirus disease-19 (COVID-19) is quite prevalent at admission and affects prognosis. Little is known about troponin trajectories and their prognostic role. We aimed to describe the early in-hospital evolution of MI and its prognostic impact.
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- Glucocorticoid therapy has been found effective in reducing mortality in hospitalized COVID-19 patients, based on a study of 706 patients from the Cardio-COVID-Italy registry.
- The study showed that patients treated with glucocorticoids had a significantly lower risk of in-hospital mortality (adjusted HR 0.44) compared to those who weren't treated, especially those with specific clinical conditions.
- The benefits of glucocorticoids were particularly noticeable in patients with poor respiratory function (lower PaO/FiO ratio and oxygen saturation) and higher levels of systemic inflammation (higher CRP levels).
Background: Contrast associated-acute kidney injury (CA-AKI) has been associated with adverse outcomes after ST-segment elevation myocardial infarction (STEMI). However, early markers of CA-AKI are still needed to improve risk stratification. We investigated the association between elevated serum uric acid (eSUA) and CA-AKI in patients with STEMI treated with primary percutaneous coronary intervention (pPCI).
View Article and Find Full Text PDFBackground And Aims: Despite elevated serum uric acid (eSUA) has been identified as independent risk factor for cardiovascular diseases, its prognostic value in the setting of ST-segment elevation myocardial infarction (STEMI) is still controversial. Although the mechanisms of this possible relationship are unsettled it has been suggested that eSUA could trigger the inflammatory response. This study sought to investigate the association between eSUA with short- and long-term mortality and with inflammatory response in patients with STEMI treated with primary percutaneous coronary intervention (pPCI).
View Article and Find Full Text PDFAims: The adoption of percutaneous stellate ganglion blockade for the treatment of drug-refractory electrical storm (ES) has been increasingly reported; however, the time of onset of the anti-arrhythmic effects, the safety of a purely anatomical approach in conscious patients and the additional benefit of repeated procedures remain unclear.
Methods And Results: This study included consecutive patients undergoing percutaneous left stellate ganglion blockade (PLSGB) in our centre for drug-refractory ES. Lidocaine, bupivacaine, or a combination of both were injected in the vicinity of the left stellate ganglion.