Double-blind multicentre, between patients comparison of indoprofen and indomethacin in rheumatoid arthritis patients under basic steroid treatment.

The study was aimed at comparing effectiveness, safety and possible steroid sparing effects of indoprofen (800 mg/day) and indomethacin (100 mg/day), in patients with classical or definite rheumatoid arthritis, in active phase, receiving basic steroid treatment at a fixed, not reducible dosage. Treatments were given in double-blind condition, for 1,3 or 6 months, and 97 patients were evaluated. A significant improvement of baseline conditions was obtained with both drugs in all variables considered for evaluation of effectiveness.

How useful is the skull x-ray examination in trauma?

Abnormalities were detected only in 24 (2.3%) of 1053 skull X-ray examinations performed in cases of suspected head trauma, at a cost of $1461 per positive finding. Only in six cases (0.