Publications by authors named "Camilo Llamoza"
Article Synopsis
- The Barcelona Clinic Liver Cancer (BCLC) staging system is crucial for treating hepatocellular carcinoma (HCC); recent updates allow for BCLC stage B patients to consider liver transplantation, while hepatectomy is now discouraged.
- A systematic review analyzed 31 studies involving 3163 patients to compare survival rates, postoperative complications, and patient selection for liver resection versus transplantation in BCLC stage B patients.
- Results showed that while resection had a 50-month survival and a 15-month recurrence-free period, data on transplantation was limited, with only one study reporting on it, indicating the need for more research in this area.
Article Synopsis
- Hepatocellular carcinoma (HCC) is a dangerous cancer often linked to chronic hepatitis C and heavy alcohol use, which can create unique protein patterns in patients.
- This study aimed to find protein biomarkers to better detect HCC in patients with cirrhosis caused by HCV infection and alcohol abuse.
- Researchers identified several proteins in plasma that showed different expressions between patients with and without HCC, with C4a emerging as a key predictor, suggesting a potential for using specific protein combinations as reliable biomarkers for HCC detection.
Background: The current methods available for screening and detecting hepatocellular carcinoma (HCC) have insufficient sensitivity and specificity, and only a low percentage of diagnosis of small tumours is based on these assays. Because HCC is usually asymptomatic at potentially curative stages, identification of biomarkers for the early detection of HCC is essential to improve patient survival.
Aim: The aim of this study was to identify candidate markers for HCC development in the plasma from hepatitis C virus (HCV)-infected cirrhotic patients.