Publications by authors named "Camille Walton"
Objective: To assess the success rate of patent ductus arteriosus (PDA) transcatheter closure in preterm infants and to describe the nature of procedural adverse events and short-term clinical status.
Study Design: All the preterm infants with PDA transcatheter closure were evaluated retrospectively between July 2019 and March 2023 in a single level III neonatal intensive care unit in France. The procedure was performed in the catheterization laboratory using venous canulation.
Article Synopsis
- - This study focuses on patients with repaired tetralogy of Fallot, particularly examining characteristics of those experiencing rapid ventricular tachycardia (VT) and the potential progression from nonrapid VT to rapid VT or ventricular fibrillation (VF).
- - Researchers analyzed data from a nationwide registry and found that out of 144 patients, 61 experienced VT or VF episodes, with 28 classified as rapid, revealing distinct clinical differences between the rapid and nonrapid groups, such as age at implantation and cardiac history.
- - The study concludes that patients with rapid VT/VF show specific clinical traits, and the consistent VT cycle lengths over time may indicate a chance for catheter ablation without needing an implantable cardioverter-defibrillator (
Background: Women with congenital heart disease at high risk for sudden cardiac death have been poorly studied thus far.
Objectives: The aim of this study was to assess sex-related differences in patients with tetralogy of Fallot (TOF) and implantable cardioverter-defibrillators (ICDs).
Methods: Data were analyzed from the DAI-T4F (French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator) cohort study, which has prospectively enrolled all patients with TOF with ICDs in France since 2010.
Therapeutic ketosis decreases methacholine hyperresponsiveness in mouse models of inherent obese asthma.
Am J Physiol Lung Cell Mol Physiol
February 2022
Obese asthmatics tend to have severe, poorly controlled disease and exhibit methacholine hyperresponsiveness manifesting in proximal airway narrowing and distal lung tissue collapsibility. Substantial weight loss in obese asthmatics or in mouse models of the condition decreases methacholine hyperresponsiveness. Ketone bodies are rapidly elevated during weight loss, coinciding with or preceding relief from asthma-related comorbidities.
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- - The study focuses on the management of anomalous aortic origin of a coronary artery, which can be linked to sudden death in young individuals, especially those with an inter-arterial course.
- - Over a 25-year period, 100 patients were diagnosed, with higher rates of syncope and sudden death among those with an inter-arterial course compared to others (23.4% vs 0%).
- - Surgical repair was performed on 61 patients, all of whom had the inter-arterial course and were asymptomatic after an average follow-up of about 5 years, suggesting that surgical intervention is a viable option even for asymptomatic cases.
Article Synopsis
- The study evaluated the effect of pulmonary valve replacement (PVR) on the incidence of ventricular arrhythmias in tetralogy of Fallot (TOF) patients who have implantable cardioverter-defibrillators (ICDs).
- Results showed that among the 165 TOF patients monitored, those who underwent PVR experienced significantly fewer appropriate ICD therapies after the surgery compared to before, indicating a reduction in arrhythmia burden.
- The findings suggest that PVR may play a crucial role in decreasing the risk of arrhythmias and highlight the importance of considering PVR in the treatment plans for high-risk TOF patients.
Background: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease, and sudden cardiac death represents an important mode of death in these patients. Data evaluating the implantable cardioverter defibrillator (ICD) in this patient population remain scarce.
Methods: A Nationwide French Registry including all patients with tetralogy of Fallot with an ICD was initiated in 2010 by the French Institute of Health and Medical Research.
Many mouse models of allergic asthma exhibit eosinophil-predominant cellularity rather than the mixed-granulocytic cytology in steroid-unresponsive severe disease. Therefore, we sought to implement a novel mouse model of antigen-driven, mixed-granulocytic, severe allergic asthma to determine biomarkers of the disease process and potential therapeutic targets. C57BL/6J wild-type, interleukin-6 knockout (IL-6-/-), and IL-6 receptor knockout (IL-6R-/-), mice were injected with an emulsion of complete Freund's adjuvant and house dust mite antigen (CFA/HDM) on .
View Article and Find Full Text PDFTo assess the outcomes of neonates prenatally diagnosed with ventricular asymmetry and not operated on within the neonatal period and to determine the risk factors for left heart obstruction occurrence at follow-up. All neonates with prenatal asymmetry of the ventricles, diagnosed from August 1993 to July 2015, not operated on within the neonatal period, were retrospectively included in the study. Left heart echocardiographic measurements at birth and at last follow-up were collected and compared.
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