Publications by Camille Poncon

Publications by authors named "Camille Poncon"

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Material and nanomechanical properties of bone structural units of cortical and trabecular iliac bone tissues from untreated postmenopausal osteoporotic women.

Delphine Farlay Guillaume Falgayrac Camille Ponçon Sébastien Rizzo Bernard Cortet

Bone Rep

December 2022

Article Synopsis

The study compared the mechanical and intrinsic properties of cortical (Ct) and trabecular (Tb) bone in iliac biopsies from untreated postmenopausal osteoporotic women to better understand their contributions to overall bone strength.* -
It was found that the indentation modulus (elasticity) and dissipated energy were higher in Ct bone compared to Tb, while hardness showed no significant difference; mineral and collagen maturity were also greater in Ct than in Tb.* -
Overall, while Ct and Tb bones exhibited distinct mechanical properties, the differences within the bone tissue types (osteonal vs. interstitial) were more pronounced than those between the two bone compartments.*

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Bone matrix quality in paired iliac bone biopsies from postmenopausal women treated for 12 months with strontium ranelate or alendronate.

Guillaume Falgayrac Delphine Farlay Camille Ponçon Hélène Béhal Marc Gardegaront

Bone

December 2021

Bone quality is altered mainly by osteoporosis, which is treated with modulators of bone quality. Knowledge of their mechanisms of action is crucial to understand their effects on bone quality. The goal of our study was to compare the action of alendronate (ALN) and strontium ranelate (SrRan) on the determinants of bone quality.