Publications by authors named "Camille Legouy"
Background: We aimed to investigate the association of intracranial complications diagnosed on neuroimaging with neurological outcomes of adults with severe pneumococcal meningitis.
Methods: We performed a retrospective multicenter study on consecutive adults diagnosed with pneumococcal meningitis requiring at least 48 h of stay in the intensive care unit (ICU) and undergoing neuroimaging, between 2005 and 2021. All neuroimaging were reanalyzed to look for intracranial complications which were categorized as (1) ischemic lesion, (2) intracranial hemorrhage (3) abscess/empyema, (4) ventriculitis, (5) cerebral venous thrombosis, (6) hydrocephalus, (7) diffuse cerebral oedema.
Article Synopsis
- Mechanical ventilation for myasthenic crisis lacks standardization and is prone to failure; a study investigated using prolonged spontaneous breathing trials (SBT) and pulmonary function tests (PFT) to improve weaning outcomes.
- Of the 126 analyzed cases, the weaning failure rate was 14.3%, notably lower when the cause of the crisis was identified, although factors like mechanical ventilation duration and infection risk influenced prolonged weaning.
- The study suggests that implementing standardized protocols could enhance extubation success, emphasizing the need for further research to validate these findings in larger trials.
Purpose Of Review: The present review summarizes the diagnostic approach to autoimmune encephalitis (AE) in the intensive care unit (ICU) and provides practical guidance on therapeutic management.
Recent Findings: Autoimmune encephalitis represents a group of immune-mediated brain diseases associated with antibodies that are pathogenic against central nervous system proteins. Recent findings suggests that the diagnosis of AE requires a multidisciplinary approach including appropriate recognition of common clinical syndromes, brain imaging and electroencephalography to confirm focal pathology, and cerebrospinal fluid and serum tests to rule out common brain infections, and to detect autoantibodies.
Objective: Our aim was to compare the prevalence of biofilm formation on antibiotic-impregnated (AIC) versus standard (SC) external ventricular drain (EVD) catheters.
Methods: From March 2018 to November 2020, all consecutive EVD catheters inserted in adult patients were included. After removal, EVD catheters were analyzed under scanning electronic microscopy, on both extraluminal and intraluminal faces.
Aims: Late auditory evoked potentials, and notably mismatch negativity (MMN) and P3 responses, can be used as part of the multimodal prognostic evaluation in post-anoxic disorders of consciousness (DOC). MMN response preferentially stems from the temporal cortex and the arcuate fasciculus. Situations with discrepant evaluations, for example MMN absent but P3 present, are frequent and difficult to interpret.
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- Scientists looked at brain activity in patients with severe brain injuries to see if they could predict if these patients would wake up.
- They used special equipment to analyze brain signals and found a new way to measure brain connections that might help doctors make better decisions.
- The study showed that this new method is linked to patients waking up and recovering, but it still needs to be tested more before being used widely.
Objectives: To describe 3-6-month neurologic outcomes of survivors of COVID-19-associated acute respiratory distress syndrome, invasively ventilated in the ICU.
Design: A bicentric prospective study during the two first waves of the pandemic (March to May and September to December, 2020).
Setting: Two academic hospital ICUs, Paris, France.
Context: Delayed awakening after sedation interruption is frequent in critically ill patients receiving mechanical ventilation.
Objectives: We aimed to investigate the association of standard electroencephalography with mortality and command following in this setting.
Design, Setting, And Patients: In a single-center study, we retrospectively analyzed standard electroencephalography performed in consecutive mechanically ventilated patients remaining unresponsive (comatose/stuporous or unable to follow commands) after sedation interruption.
Purpose: Alert intensivists about the diagnostic pitfalls arising from hyperammonemia due to Ureaplasma infections in post-transplant patients.
Materials And Methods: Clinical observation of one patient.
Case Report: A 65-year-old female with a medical history of semi-recent kidney transplant was admitted to the Intensive Care Unit for refractory status epilepticus.
Cerebellar vermis hypermetabolism in opsoclonus myoclonus without onconeural antibodies.
Neurol Neuroimmunol Neuroinflamm
December 2015