Publications by authors named "Camille Hoteit"
Int J Mol Sci
December 2020
Article Synopsis
- HDLs have protective effects on the endothelial cells, which are crucial for maintaining blood-brain barrier (BBB) integrity during acute ischemic strokes.
- The study involved using mice with and without the SR-BI receptor to observe the effects of HDLs on infarct volume and BBB breakdown after a stroke.
- Results showed that while HDLs reduced brain damage and BBB leakage in normal mice, these benefits were diminished in mice lacking the SR-BI receptor on endothelial cells, highlighting SR-BI's role in mediating HDL's neuroprotective effects.
