Publications by authors named "Camilla de Souza"
The biodiversity of Brazil provides an excellent climate and favorable pollination conditions for L., especially in the Eastern Amazon region, which boasts vast floral wealth, including an abundance of açaí () flowers and fruits. In the present study, seven types of honey were evaluated: three containing floral nectar from açaí (Açaí honey) collected in the Eastern Amazon region (Açaí honey from Breu Branco (AH1 and AH2) and Açaí honey from Santa Maria (AH3), both from the state of Pará, Brazil) and four honeys from different regions of Brazil (Aroeira honey from Minas Gerais, Cipó-Uva honey from Distrito Federal, Mangue honey from Pará, and Timbó honey from Rio Grande do Sul).
View Article and Find Full Text PDFBackground: Mitochondrial carriers (MCs) can deeply affect the intracellular flux distribution of metabolic pathways. The manipulation of their expression level, to redirect the flux toward the production of a molecule of interest, is an attractive target for the metabolic engineering of eukaryotic microorganisms. The non-conventional yeast Yarrowia lipolytica is able to use a wide range of substrates.
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- The study investigated the presence of specific mRNAs related to kidney function (nephrin and podocin) in the urine of dogs with chronic kidney disease (CKD) compared to healthy dogs.
- A total of 24 dogs participated, with 14 diagnosed with CKD, categorized into two groups based on the severity of their condition.
- Results showed that while both mRNAs were found in all groups, higher detection rates were observed in dogs with early-stage CKD (stages 1 and 2) and lower rates in those with advanced stages (3 and 4).
Low-Dose Coconut Oil Supplementation Induces Hypothalamic Inflammation, Behavioral Dysfunction, and Metabolic Damage in Healthy Mice.
Mol Nutr Food Res
May 2021
Scope: Coconut oil (CO) diets remain controversial due to the possible association with metabolic disorder and obesity. This study investigates the metabolic effects of a low amount of CO supplementation.
Methods And Results: Swiss male mice are assigned to be supplemented orally during 8 weeks with 300 µL of water for the control group (CV), 100 or 300 µL of CO (CO100 and CO300) and 100 or 300 µL of soybean oil (SO; SO100 and SO300).
Article Synopsis
- Yarrowia lipolytica IMUFRJ 50682 is a Brazilian strain with potential for bioconversion, and the study aimed to enhance its capabilities using CRISPR/Cas9 technology to create irreversible auxotrophic mutants by targeting the URA3 gene.
- The disruption of the URA3 gene showed a disruption efficiency of 5 to 28%, resulting in mutants that lost a significant coding sequence, and a fluorescent phenotype was successfully introduced with high cloning rates.
- The engineered ura3Δ mutants were tested for β-carotene synthesis, producing between 30.54-50.06 mg/L, demonstrating their potential as effective platforms for producing valuable chemicals.
Aims: To determine the expression of the cyclooxygenase-2 () gene in patients with breast cancer attended at the Centro Universitário Saúde ABC/Faculdade de Medicina do ABC (CUS-ABC/FMABC) outpatient clinic. Breast cancer is the most common cancer in women worldwide. More than two million new cases are reported annually.
View Article and Find Full Text PDFObjective: This article aimed to evaluate in vitro the efficiency of Pro Seal fluoride sealant application in the prevention of white spot lesions around orthodontic brackets.
Material And Methods: Brackets were bonded to the buccal surface of bovine incisors, and five groups were formed (n = 15) according to the exposure of teeth to oral hygiene substances and the application of enamel sealant: G1 (control), only brushing was performed with 1.450 ppm fluoride; G2 (control) brushing associated with the use of mouthwash with 225 ppm fluoride; G3, only Pro Seal sealant application was performed with 1.