Versatility of composite grafts for nasal defects - a case series.

This retrospective study describes the reconstruction of 18 nasal defects with chondrocutaneous (composite) grafts. Composite grafts are versatile one-stage options for defects ≤2.5 cm at the lower third of the nose and are particularly useful in reconstruction of small full-thickness defects and superficial defects bordering or involving the alar rim.

[Accidential consumption of wart remover].

Not seldom do people buy medicine abroad while on business or holiday, where international labelling is less than optimal. Once home, the medication is often kept alongside every-day products, sometimes resulting in home accidents due to a confusion of products. In this case a six-month-old girl was administered five drops of monochloroacetic acid orally as a result of mistaking a bottle of D-vitamin with a bottle of acid for the removal of warts.

Association between organic dietary choice during pregnancy and hypospadias in offspring: a study of mothers of 306 boys operated on for hypospadias.

Purpose: The etiology of hypospadias is poorly understood. Exposure to pesticides has been considered a risk factor, although findings are inconsistent. Diet constitutes a significant exposure route for pesticides, and pesticide residues are more frequently reported in conventional than organic food products.

A novel mutation in IRF6 resulting in VWS-PPS spectrum disorder with renal aplasia.

Popliteal pterygium syndrome (PPS) and Van der Woude syndrome (VWS) are caused by mutations in the gene interferon regulatory factor 6 (IRF6). Skeletal, genital malformations and involvement of the skin occur in PPS and orofacial clefting and lip pits occur in both. We report on a patient with unilateral cleft lip and palate, ankyloblepharon, paramedian lip pits, unilateral renal aplasia, and a coronal hypospadias.

Self-rated health and semen quality among 3,457 young Danish men.

Objective: To study the relationship between self-rated health (SRH) and semen quality.

Design: Cross-sectional study of men attending a compulsory physical examination to determine their fitness for military service from 1996 to 2005.

Setting: Young men were approached when they were summoned for a compulsory physical examination to determine their fitness for military service in two major Danish cities.

[A ten-year retrospective study of patients operated for hypospadias].

Introduction: Retrospectively we evaluated the surgical treatment of all primary operations for hypospadias performed at the Department of Plastic- and Reconstructive Surgery, Herlev University Hospital, over a period of ten years. During this time we changed the concept of surgical procedure from various two-stage techniques to a new one-stage modification (Scuderi's vascularised vertical preputial island flap combined with a triangular flap glanuloplasty and other refinements). Secondly, we evaluated the pre- and postoperative examination.

Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population.

Little is known the about the reproductive health of offspring after fertility treatment. In 2001-2005, the authors approached young Danish men attending a compulsory physical examination to determine their fitness for military service. A total of 1,925 men volunteered, delivered a semen sample, had a physical examination performed and a blood sample drawn, and responded to a questionnaire.

Twin pregnancy possibly associated with high semen quality.

Background: Recent studies found an association between a long waiting time to pregnancy (TTP) and reduced probability of twinning and a reduced dizygotic (DZ) twinning rate in subfertile men. However, it remains unsolved whether semen quality is associated with twin offspring. We therefore studied the semen quality in a group of fathers of naturally conceived twins.

Testicular dysgenesis syndrome: possible role of endocrine disrupters.

The testicular dysgenesis syndrome (TDS) hypothesis proposes that the four conditions cryptorchidism, hypospadias, impaired spermatogenesis and testis cancer may all be manifestations of disturbed prenatal testicular development. The TDS hypothesis is based on epidemiological, clinical and molecular studies, all suggestive of an interrelation between the different symptoms. The aetiology of TDS is suspected to be related to genetic and/or environmental factors, including endocrine disrupters.

Coordinated European investigations of semen quality: results from studies of Scandinavian young men is a matter of concern.

For many years it has been acknowledged that Danish and Norwegian men have one of the highest risks in the world for testicular cancer in sharp contrast to neighbouring Baltic men from Finland, Estonia and Lithuania. As an association between poor semen quality and testicular cancer has been established, it was suggested that men from high-risk testicular cancer areas would be more likely to have poor semen quality. However, previous studies were not able to elucidate this question due to their retrospective nature.