Developmental delay during eye morphogenesis underlies optic cup and neurogenesis defects in zebrafish mutants.

Shaping the vertebrate eye requires evagination of the optic vesicles. These vesicles subsequently fold into optic cups prior to undergoing neurogenesis and allocating a population of late progenitors at the margin of the eye. encodes a protein of unknown biological function expressed in the developing optic vesicles, and loss of function results in malformed eyes.