Publications by authors named "Camila Tainah Da Silva"
Article Synopsis
- * The study aimed to identify genes related to cell differentiation and proliferation that are differently expressed in ccRCC, using techniques like quantitative PCR (qPCR) and immunohistochemistry.
- * Key findings include the underexpression of genes occludin (OCLN) and growth arrest-specific 1 (GAS1), which may be regulated by specific microRNAs, and the significant overexpression of solute carrier family 2 member 1 (SLC2A1) in ccRCC samples.
Correction: Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation.
Fernanda Molognoni Fabiana Henriques Machado de Melo Camila Tainah da Silva Miriam Galvonas Jasiulionis
PLoS One
September 2015
Article Synopsis
- The text mentions a correction to an article that can be found using the Digital Object Identifier (DOI) 10.1371/journal.pone.0081937.
- Corrections in academic articles are made to address errors or inaccuracies that may affect the study's findings or conclusions.
- This highlights the importance of accuracy and reliability in academic publishing, as corrections help maintain the integrity of the research.
Article Synopsis
- A model for studying melanoma development was created by exposing non-tumorigenic melanocyte cells to repeated cycles of conditions that hinder their attachment.
- The research found that increased levels of superoxide, a reactive oxygen species, lead to changes in DNA methylation and expression of specific genes, contributing to cell transformation.
- The activation of the Ras/Rac1/ERK signaling pathway was identified as a key factor in this process, indicating that environmental stressors like superoxide might trigger early events in melanoma progression.*