Publications by authors named "Camila Rodrigues Ferraz"
Lisdexamfetamine dimesylate-exposition in male rats during the peripubertal period impairs inflammatory mechanisms, antioxidant activity, and apoptosis process in kidneys of male pubertal rats.
J Biochem Mol Toxicol
August 2024
Article Synopsis
- Lisdexamfetamine dimesylate (LDX), a drug for ADHD, hasn't been studied for its potential toxic effects on kidneys, which is the focus of this research.
- The study involved male Wistar rats treated with LDX to assess kidney health through various parameters including cell death, inflammation, and oxidative stress.
- Findings revealed increased cell death and inflammation in the kidneys of LDX-treated rats, but a normal functioning antioxidant system, indicating significant renal changes during the peripubertal period.
Modulation of Broiler Intestinal Changes Induced by and Deoxynivalenol through Probiotic, Paraprobiotic, and Postbiotic Supplementation.
Toxins (Basel)
January 2024
Deoxynivalenol (DON) is a predisposing factor for necrotic enteritis. This study aimed to investigate the effects of a DON and (CP) challenge on the intestinal morphology, morphometry, oxidative stress, and immune response of broilers. Additionally, we evaluated the potential of a spp.
View Article and Find Full Text PDFWound healing has been extensively studied through the lens of inflammatory disorders and cancer, but limited attention has been given to hematophagy and arthropod-borne diseases. Hematophagous ectoparasites, including ticks, subvert the wound healing response to maintain prolonged attachment and facilitate blood-feeding. Here, we unveil a strategy by which extracellular vesicles (EVs) ensure blood-feeding and arthropod survival in three medically relevant tick species.
View Article and Find Full Text PDFThe aim of this study was to evaluate the oxidative stress in ovaries and corpus luteum (CL) of females and the oxidant effect of CL in ovarian tissues in regions near, intermediate, or distant from it. Ovaries (n=12) of Nelore heifers (n=6) were collected from a slaughterhouse and fragmented. Experiment 1, each ovary was obtained from three fragments, resulting in 18 fragments of ovaries with CL (OV+CL) and another 18 fragments of ovaries without CL (OV-CL).
View Article and Find Full Text PDFPain is a common symptom associated with disorders involving the orofacial structures. Most acute orofacial painful conditions are easily recognized, but the pharmacological treatment may be limited by the adverse events of current available drugs and/or patients' characteristics. In addition, chronic orofacial pain conditions represent clinical challenges both, in terms of diagnostic and treatment.
View Article and Find Full Text PDFImpact of the antioxidant quercetin on morphological integrity and follicular development in the in vitro culture of Bos indicus female ovarian fragments.
In Vitro Cell Dev Biol Anim
October 2021
Article Synopsis
- The study examined how quercetin affects the growth and health of bovine ovarian fragments, focusing on their morphology and oxidative stress levels using 12 ovaries from Nelore heifers.* -
- Quercetin was tested at concentrations of 0, 10, 25, and 50 μg/mL over 5 or 10 days, with 25 μg/mL yielding the highest number of healthy and developing follicles along with improved antioxidant effects after 10 days.* -
- Results showed that while 25 μg/mL quercetin significantly preserved the integrity of developing follicles, there were no notable changes in reactive oxygen species or lipid oxidative degradation compared to non-cultivated controls.*
Article Synopsis
- Zika virus (ZIKV) is mostly spread to people by mosquitoes and wasn’t a big deal until outbreaks happened in places like Yap Island and Brazil.
- Most people who get ZIKV don't feel sick, but in some cases, it can cause serious problems for babies and adults, leading to issues like small heads in infants and nerve problems in adults.
- Scientists are looking into natural compounds called flavonoids as possible treatments or vaccines for ZIKV since they're safe for humans, but more research is needed to know if they can really help.
We investigated the antidiarrhoeic effect of the aqueous extract of Annona crassiflora leaves (AEAC). The AEAC decreased the diarrhoeic stools and enteropooling induced by castor oil, without altering total faecal output; moreover, the distance travelled by charcoal meal in the intestine was increased. Twenty-eight compounds were identified by LC-DAD-MS in the AEAC, including flavonoids, alkaloids and proanthocyanidins.
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