Publications by authors named "Camila Rodrigues Chaves"
Nowadays, even in light of all the massive advances in cell biology, we still find some cellular structures that are not entirely understood. Among those, we highlight the costa, a structure from the mastigont system existent only in some members of the orders Trichomonadida and Tritrichomonadida, including the pathogens of venereal diseases in humans and cattle, Trichomonas vaginalis (T. vaginalis) and Tritrichomonas foetus (T.
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- Aging is associated with functional decline and mitochondrial dysfunction, largely due to decreased NAD levels and increased activity of the enzyme CD38.
- Research indicates that inhibiting CD38 can improve mitochondrial function in various tissues, but its specific impact on NAD levels and metabolism in the aging brain is still unclear.
- This study reveals that while CD38 does not affect overall NAD levels or mitochondrial oxygen consumption in aging brains, it plays a crucial role in regulating hydrogen peroxide production related to mitochondrial function, suggesting a new link between CD38 and brain energy metabolism in aging.