[Clinical features of systemic sclerosis and association with antitopoisomerase-1 antibody and centromere pattern of antinuclear antibody].

Objective: To describe clinical features of patients with systemic sclerosis (SSc) and associate them with antitopoisomerase-1 antibody and centromere pattern of antinuclear antibody.

Methods: We evaluated 50 patients who met SSc screening criteria of the American College of Rheumatology, and classified as limited cutaneous SSc and diffuse cutaneous SSc. Clinical history, physical examination and laboratory tests were evaluated: cutaneous, vascular, gastrointestinal, renal, pulmonary and cardiac involvement, in addition to autoantibodies.

[Systemic lupus erythematosus presenting as autoimmune parotitis and pancreatitis - Case Report].

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease which can present from classical to atypical forms. We discuss the case of a young lady of 29 years-old recently diagnosed with SLE that manifested parotitis and pancreatitis.

[Skin manifestation in systemic sclerosis].

Objective: To assess cutaneous manifestations in a population of patients with systemic sclerosis (SSc).

Method: The study population was constituted by 50 patients with a diagnosis of SSc, according to the classification criteria for SSc established by the American College of Rheumatology. According to the criteria proposed by LeRoy and cols.