Publications by authors named "Camila F Borgognoni"
Article Synopsis
- Cyclometalated iridium (Ir) complexes are potential agents for biomedical use but face issues due to high cytotoxicity, limiting their effectiveness in imaging and sensing.
- Laponite serves as a promising carrier, providing biocompatibility and stability while effectively adsorbing various functional molecules.
- This approach reduces cytotoxicity, enhances cell uptake, and improves luminescent properties, potentially broadening the use of metal-organic complexes in biomedical applications.
Article Synopsis
- The study explores how titanium dioxide (TiO2) nanoparticles affect cytokine secretion in human macrophages, revealing that high concentrations stimulate multiple cytokines while low levels mainly increase IL-6.
- At concentrations below 1 μg/ml, the presence of a protein corona around the TiO2 nanoparticles triggers IL-6 secretion, which is linked to autoimmune disease development.
- These findings highlight potential health risks associated with using TiO2 nanoparticles in medical and industrial applications, indicating the need for careful consideration of their effects.
Purpose: Biomaterials have been widely used in the field of regenerative medicine. Bovine pericardium tissue has been successfully used as a bioprosthetic material in manufacturing heart valves, but studies concerning the tissue are ongoing in order to improve its storage, preservation and transportation. This article provides an overview of the characteristics of bovine pericardium tissue chemically treated after the freeze-drying process.
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