Publications by authors named "Camila Chavero"
Article Synopsis
- * The study evaluated the effects of poly(allylamine hydrochloride) (PAH)-based nanoparticles on antigen-presenting cells and found that they boosted important immune responses, increasing the expression of CD86 and MHCII and promoting the production of cytokines IL-1β and IL-18.
- * Results indicated that systemic administration of Np-OVA led to a strong immune response in mice, characterized by increased specific antibodies and activation of T-helper cells, suggesting potential for new vaccine development against various diseases.
Designing effective drug nanocarriers that are easy to synthesize, robust, and nontoxic is a significant challenge in nanomedicine. Polyamine-multivalent molecule nanocomplexes are promising drug carriers due to their simple and all-aqueous manufacturing process. However, these systems can present issues of colloidal instability over time and cellular toxicity due to the cationic polymer.
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